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What causes abdominal pain, itching and loss of appetite? 21 possible conditions

See a list of possible causes in order from the most common to the least.



Hepatitis is swelling and inflammation of the liver. It's usually caused by a viral infection. There are several types of hepatitis, including: A, B, C, D, and E. Symptoms may not occur until liver damage occurs.

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Acute Pancreatitis

Acute pancreatitis is an inflammation in the pancreas, which causes pain and swelling in the upper left side of the abdomen, nausea, and burping.

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Gallstones are hard deposits in the gallbladder that can eventually block the exiting bile ducts. Abdominal pain, fever, itchy skin, and jaundice are possible symptoms.

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Drug Allergy Overview

This condition is considered a medical emergency. Urgent care may be required.

A drug allergy is an allergic reaction to a medication. Your immune system identifies the drug as foreign and acts to eliminate it from your body.

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Alcoholic Liver Disease

Damage to the liver from excessive drinking can lead to ALD. Years of alcohol abuse cause the liver to become inflamed and swollen. This damage can also cause scarring known as cirrhosis. Cirrhosis is the final stage o...

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Chemical Burns

This condition is considered a medical emergency. Urgent care may be required.

Chemical burns occur when the skin or eyes come into contact with irritants, such as acids or bases. Symptoms vary, but skin reactions, pain or numbness are common.

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Hepatitis A

Hepatitis A (HAV) is a short-term type of hepatitis. It usually requires no treatment, but symptoms include fever, nausea, jaundice, and itchy skin, among others.

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Cirrhosis is severe scarring and poor function of the liver caused by long-term exposure to toxins such as alcohol or viral infections. Certain medications and disorder can also cause cirrhosis.

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Hepatitis B

Hepatitis B is liver inflammation caused by the hepatitis B virus (HBV). It can be chronic or acute, but most cases are chronic. This disease is easily spread through blood, saliva, and other body fluids.

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Hepatitis E

The hepatitis E virus is spread most often by contaminated drinking water. It is different from the hep-A virus but the symptoms are similar. Most cases clear up on their own after a few weeks. In other cases, the viru...

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Hepatitis D

Hepatitis D is an infection of the hepatitis D virus that causes your liver to swell and is uncommon in the United States. It is almost always contracted by people with hepatitis B.

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Hepatitis C

Hepatitis C is a disease that causes inflammation and infection in the liver. Symptoms of chronic cases may not be obvious at first, whereas acute hepatitis C sets in quickly after exposure to the virus.

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Infectious Mononucleosis

Infectious mononucleosis, or "mono," is a group of symptoms caused by the Epstein-Barr virus. One potential symptom is a pink rash that looks like the measles.

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Pancreatic Cancer

Pancreatic cancer is cancer of the pancreas, an organ that secretes an enzyme that breaks down fats, carbs, and proteins. Pancreatic cancer can obstruct the outflow of bile from the liver and causes yellow skin.

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Sarcoidosis is an inflammatory disease that causes granulomas, which are clumps of immune cells, to form in different organs. A skin rash is one symptom of sarcoidosis of the skin.

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In hyperparathyroidism, the parathyroid glands make too much of their hormone. It affects a number of body systems and can cause skin changes, including brittle nails and itching.

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Yellow fever

Yellow fever is a serious, potentially deadly flu-like disease spread by mosquitoes. It's found mostly in Africa and South America. Symptoms of stage 3 yellow fever include abdominal pain, vomiting, and jaundice.

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Hookworm Infections

Hookworms are parasites that affect the small intestine and lungs. The first sign of infection is usually a rash where the parasite entered the skin, followed by diarrhea.

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Biliary (Bile Duct) Obstruction

A biliary obstruction blocks the bile ducts, which carry bile to the small intestine for digestion and waste removal. An obstruction can be caused by many factors, including gallstones, inflammation, cysts, or tumors.

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Thalassemia is an inherited blood disorder that results in excessive destruction of red blood cells (anemia). Symptoms depend on its severity, and can range from minor anemia to enlargement of organs or fetal death.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.