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What causes abdominal pain and general weakness? 68 possible conditions

See a list of possible causes in order from the most common to the least.


Celiac Disease (Gluten Intolerance)

Celiac disease is a digestive disorder caused by an immune reaction to gluten. Symptoms vary but can include arthritis, fatigue, and abdominal symptoms.

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Idiopathic Autoimmune Hemolytic Anemia

Autoimmune hemolytic anemia (AIHA) is a group of blood disorders that occur when red blood cells are destroyed faster than they're produced. Symptoms include weakness, shortness of breath, rapid heart rate, and others.

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Liver Cancer

Liver cancer causes destruction of liver cells and interferes with the ability of the liver to function normally. Cancer that originates in the liver can spread from the liver to other parts of the body.

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Amebiasis is a parasitic infection, common in the tropics and caused by contaminated water. Symptoms can be severe and usually start 1-4 weeks after exposure.

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The War of Cells: Graft vs. Host Disease

Graft vs. Host Disease is a common reaction that develops after an allogeneic bone marrow transplant. It usually goes away after the transplant has become established. It causes symptoms throughout the body's systems.

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Burkitt's Lymphoma

Burkitt's lymphoma is a relatively rare and aggressive form of non-Hodgkin's lymphoma, a type of cancer of the lymphatic system. It's most common in children living in sub-Saharan Africa.

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Hookworm Infections

Hookworms are parasites that affect the small intestine and lungs. The first sign of infection is usually a rash where the parasite entered the skin, followed by diarrhea.

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What You Need to Know About Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal nocturnal hemoglobinuria is a rare disorder that causes red blood cells to break down sooner than normal. This can lead to symptoms that range from minimal (urine discoloration) to severe (stroke).

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West Nile Virus Infection (West Nile Fever)

Spread by mosquitos, West Nile virus symptoms can vary in severity. Diarrhea and abdominal pain usually appears within two weeks of infection.

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Leishmaniasis is a parasitic disease caused by the Leishmania parasite found in sand flies.

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Hepatitis D

Hepatitis D is an infection of the hepatitis D virus that causes your liver to swell and is uncommon in the United States. It is almost always contracted by people with hepatitis B.

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Hepatitis C

Hepatitis C is a disease that causes inflammation and infection in the liver. Symptoms of chronic cases may not be obvious at first, whereas acute hepatitis C sets in quickly after exposure to the virus.

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Angina Pectoris

Learn about stable angina and what causes it. Find information on stable angina symptoms, risk factors, diagnosis, and treatment.

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Thalassemia is an inherited blood disorder that results in excessive destruction of red blood cells (anemia). Symptoms depend on its severity, and can range from minor anemia to enlargement of organs or fetal death.

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Cystic Fibrosis

Cystic fibrosis is a recessive genetic disorder that affects cells that produce mucous, sweat, and digestive juices. It may cause severe problems in the lungs, pancreas, liver, and intestine

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Tuberculosis (TB) is a highly infectious disease that primarily affects the lungs. A severe and long-lasting cough, fever, and night sweats could indicate an active TB infection.

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Learn about sarcoidosis and its causes, symptoms, diagnosis, treatment, and potential complications.

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Brucellosis is a rare disease usually spread through ingesting infected raw meat and unpasteurized milk. Back pain, lethargy, chills, and fever may occur and could lead to complications.

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Diabetic Ketoacidosis

This condition is considered a medical emergency. Urgent care may be required.

Diabetic ketoacidosis (DKA) is a serious complication that stems from diabetes. If you don't have enough insulin to help your body process sugars (glucose), your body will start burning fat to fuel itself. As a result...

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G6PD Deficiency

Glucose-6-phosphate dehydrogenase(G6PD) deficiency is a genetic abnormality that leads to an inadequate amount of the necessary enzyme. Without enough G6PD, red blood cells can be destroyed, leading to anemia.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.