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What causes abdominal pain, general weakness and joint pain? 18 possible conditions

See a list of possible causes in order from the most common to the least.



Leukemia is a cancer of the blood cells. Excessive sweating at night, fatigue, weight loss, bone pain, and easy bleeding or bruising are signs of this disease.

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Rheumatic Fever

Rheumatic fever is a possible and potentially serious complication of strep throat. It tends to occur in children between five and 15 years old. Rash is one possible sign of this condition.

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Hepatitis refers to an inflammatory condition of the liver. It's commonly caused by a viral infection, but there are other possible causes of hepatitis.

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Infectious Mononucleosis

Infectious mononucleosis, or "mono," is a group of symptoms caused by the Epstein-Barr virus. One potential symptom is a pink rash that looks like the measles.

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Learn about sarcoidosis and its causes, symptoms, diagnosis, treatment, and potential complications.

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Ulcerative Colitis

Ulcerative colitis is an inflammatory bowel disease. It occurs when the lining of the large intestine (colon or bowel) and the rectum become inflamed.

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Necrotizing Vasculitis

This condition is considered a medical emergency. Urgent care may be required.

Necrotizing vasculitis is the inflammation of blood vessel walls. It can interrupt blood flow, causing skin, muscle, and blood vessel damage, and death of tissues and organs. Its symptoms can affect the entire body.

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Sickle Cell Anemia

Sickle cell anemia is a genetic disease that causes red blood cells to have an abnormal shape, causing blood flow problems. This can lead to tissue damage and pain, as well as enlarged spleen, anemia, and other symptoms.

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Hepatitis A

Hepatitis A (HAV) is a short-term type of hepatitis. It usually requires no treatment, but symptoms include fever, nausea, jaundice, and itchy skin, among others.

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Hepatitis B

Hepatitis B is liver inflammation caused by the hepatitis B virus (HBV). It can be chronic or acute, but most cases are chronic. This disease is easily spread through blood, saliva, and other body fluids.

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Ebola Virus and Disease

This condition is considered a medical emergency. Urgent care may be required.

Ebola disease is a rare, often fatal illness. One of its late-stage symptoms is a bleeding rash over the entire body.

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Hepatitis D

Hepatitis D is an infection of the hepatitis D virus that causes your liver to swell and is uncommon in the United States. It is almost always contracted by people with hepatitis B.

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Hepatitis C

Hepatitis C is a disease that causes inflammation and infection in the liver. Symptoms of chronic cases may not be obvious at first, whereas acute hepatitis C sets in quickly after exposure to the virus.

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West Nile Virus Infection (West Nile Fever)

Spread by mosquitos, West Nile virus symptoms can vary in severity. Diarrhea and abdominal pain usually appears within two weeks of infection.

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Brucellosis is a rare disease usually spread through ingesting infected raw meat and unpasteurized milk. Back pain, lethargy, chills, and fever may occur and could lead to complications.

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In hyperparathyroidism, the parathyroid glands make too much of their hormone. It affects a number of body systems and can cause skin changes, including brittle nails and itching.

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Polyarteritis Nodosa

Polyarteritis nodosa (PAN) is a condition that causes swollen arteries. It primarily affects small and medium-sized arteries, which can become inflamed or damaged. This is a serious disease of the blood vessels cause...

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Hemochromatosis causes a build-up of iron. This can cause serious health problems, since the body cannot get rid of the excess iron. On average, people absorb around 10 percent of the iron contained in food. This amoun...

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.