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What causes abdominal pain, diarrhea and general weakness? 19 possible conditions

See a list of possible causes in order from the most common to the least.


Food Poisoning

This condition is considered a medical emergency. Urgent care may be required.

Food poisoning occurs when you consume foods contaminated with bacteria, viruses, or parasites. Symptoms are usually uncomfortable but not severe.

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Lactose Intolerance

Lactose intolerence occurs when a person's small intestine can't break down lactose, an enzyme found in dairy foods. The condition can cause many gastrointestinal symptoms.

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PMS (Premenstrual Syndrome)

PMS symptoms start five to 11 days before menstruation and typically go away once menstruation begins. The cause of PMS is unknown.

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Ulcerative Colitis

Ulcerative colitis is an inflammatory bowel disease. It occurs when the lining of the large intestine (colon or bowel) and the rectum become inflamed.

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Celiac Disease (Gluten Intolerance)

Celiac disease is a digestive disorder caused by an immune reaction to gluten. Symptoms vary but can include arthritis, fatigue, and abdominal symptoms.

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Crohn’s Disease

Crohn's disease is a chronic bowel disease that causes severe inflammation of the digestive tract. It is associated with abdominal pain, diarrhea, and may affect your quality of life. Crohn's disease is characterized b...

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Colorectal (Colon) Cancer

Colorectal cancer is a cancer that originates in the rectum or colon. Both of these organs are located at the lower portion of your digestive system. The colon is at the end of the large intestine and the rectum is a...

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Amebiasis is a parasitic infection, common in the tropics and caused by contaminated water. Symptoms can be severe and usually start 1-4 weeks after exposure.

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Colitis is inflammation of the colon, often causing discomfort and pain in the abdomen, as well as other gastrointestinal symptoms. Colitis has many possible causes, which determine the type.

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Cystic Fibrosis

Cystic fibrosis is a recessive genetic disorder that affects cells that produce mucous, sweat, and digestive juices. It may cause severe problems in the lungs, pancreas, liver, and intestine

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E. coli Infection

E. coli is a type of bacteria normally found in intestines. But certain kinds of E. coli can cause infection and severe symptoms like diarrhea and dehydration.

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Ebola Virus and Disease

This condition is considered a medical emergency. Urgent care may be required.

Ebola disease is a rare, often fatal illness. One of its late-stage symptoms is a bleeding rash over the entire body.

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Addison’s Disease

Addison's disease occurs when the adrenal cortex is damaged and the adrenal glands don't produce enough of the steroid hormones cortisol and aldosterone.

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Pancreatic Cancer

Pancreatic cancer is cancer of the pancreas, an organ that secretes an enzyme that breaks down fats, carbs, and proteins. Pancreatic cancer can obstruct the outflow of bile from the liver and causes yellow skin.

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The War of Cells: Graft vs. Host Disease

Graft vs. Host Disease is a common reaction that develops after an allogeneic bone marrow transplant. It usually goes away after the transplant has become established. It causes symptoms throughout the body's systems.

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Hookworm Infections

Hookworms are parasites that affect the small intestine and lungs. The first sign of infection is usually a rash where the parasite entered the skin, followed by diarrhea.

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West Nile Virus Infection (West Nile Fever)

Spread by mosquitos, West Nile virus symptoms can vary in severity. Diarrhea and abdominal pain usually appears within two weeks of infection.

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Leishmaniasis is a parasitic disease caused by the Leishmania parasite found in sand flies.

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Trichinosis is a roundworm that can infect humans when they eat certain undercooked meats. Rashes are a possible symptom of trichinosis after the larvae enter the muscle tissue.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.