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What causes abdominal pain, back pain and fatigue? 15 possible conditions

See a list of possible causes in order from the most common to the least.



Bleeding or spotting, increased need to urinate, tender breasts, fatigue, nausea, and missed period are signs of pregnancy.

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PMS (Premenstrual Syndrome)

PMS symptoms start five to 11 days before menstruation and typically go away once menstruation begins. The cause of PMS is unknown.

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Pelvic Inflammatory Disease (PID)

Pelvic inflammatory disease (PID) is an infection of the reproductive organs in women. It's marked by pain in the abdomen, especially during urination or sex.

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Endometriosis is a disorder in which the tissue that forms the lining of your uterus grows outside of your uterine cavity. The lining is called the endometrium.

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In hyperparathyroidism, the parathyroid glands make too much of their hormone. It affects a number of body systems and can cause skin changes, including brittle nails and itching.

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Pyelonephritis is an inflammation of the kidney and upper urinary tract. Symptoms include flushed skin, back pain, fever, and nausea.

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Ovarian Cancer

The ovaries are small, almond-shaped organs located on either side of the uterus that produce eggs. As the disease progresses, symptoms include back pain and indigestion.

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Dissection of the Aorta

This condition is considered a medical emergency. Urgent care may be required.

The aorta is a large artery that carries blood out of your heart. If you experience a dissection of the aorta, it means that blood has entered the wall of the artery, between the inner and middle layers. This can happe...

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Liver Cancer

Liver cancer causes destruction of liver cells and interferes with the ability of the liver to function normally. Cancer that originates in the liver can spread from the liver to other parts of the body.

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Pancreatic Cancer

Pancreatic cancer is cancer of the pancreas, an organ that secretes an enzyme that breaks down fats, carbs, and proteins. Pancreatic cancer can obstruct the outflow of bile from the liver and causes yellow skin.

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What You Need to Know About Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal nocturnal hemoglobinuria is a rare disorder that causes red blood cells to break down sooner than normal. This can lead to symptoms that range from minimal (urine discoloration) to severe (stroke).

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West Nile Virus Infection (West Nile Fever)

Spread by mosquitos, West Nile virus symptoms can vary in severity. Diarrhea and abdominal pain usually appears within two weeks of infection.

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Chronic Pancreatitis

Chronic, or long-term, pancreatitis is an inflammation of your pancreas that impairs your body's ability to digest food and regulate blood sugar.

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Brucellosis is a rare disease usually spread through ingesting infected raw meat and unpasteurized milk. Back pain, lethargy, chills, and fever may occur and could lead to complications.

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Transfusion Reactions

A transfusion reaction is a rare condition that occurs when a person receives a transfusion with blood that is not matched to their blood type. This may cause symptoms such as back pain, fever, fainting, or dizziness.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.