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Drug Notebook

FDA Alerts

    Suicidality
  • Antidepressants may increase risk of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults (18–24 years of age) with major depressive disorder and other psychiatric disorders; balance this risk with clinical need. Trimipramine is not approved for use in pediatric patients. (See Pediatric Use under Cautions.)
  • In pooled data analyses, risk of suicidality was not increased in adults >24 years of age and apparently was reduced in adults ≥65 years of age with antidepressant therapy compared with placebo.
  • Depression and certain other psychiatric disorders are themselves associated with an increased risk of suicide.
  • Appropriately monitor and closely observe all patients who are started on trimipramine therapy for clinical worsening, suicidality, or unusual changes in behavior; involve family members and/or caregivers in this process. (See Worsening of Depression and Suicidality Risk and Pediatric Use under Cautions.)

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trimipramine
(trye MI pra meen)
OP 719 | 50 mgOP 719   50 mg
bottle, 100 each Trimipramine Maleate 50mg, Oral capsule, blue, orange, oblong-shaped, side 1:OP 719
OP 720 | 100 mgOP 720   100 mg
bottle, 100 each Trimipramine Maleate 100mg, Oral capsule, blue, white, oblong-shaped, side 1:OP 720
OP 718 | 25 mgOP 718   25 mg
bottle, 100 each Trimipramine Maleate 25mg, Oral capsule, blue, yellow, oblong-shaped, side 1:OP 718
A-293 A-293 | 25 mgA-293 A-293   25 mg
bottle, 90 each Trimipramine Maleate 25mg, Oral capsule, blue, opaque, yellow, oblong-shaped, side 1:A-293 A-293
A-294 A-294 | 50 mgA-294 A-294   50 mg
bottle, 90 each Trimipramine Maleate 50mg, Oral capsule, blue, opaque, orange, oblong-shaped, side 1:A-294 A-294
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