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Drug Notebook

Generic Name: quinidine

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Quin-G, Quinidine Sulfate Dihydrate, Cardioquin, Quinidine Gluconate, Quinora, Quinidine Sulfate ER, Quinaglute Dura-Tabs, Quin-Release, Quinidine Gluconate ER, Quinidex Extentabs, Quinidine Sulfate
An antiarrhythmic agent - It helps make your heart beat regularly
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FDA Alerts

    Mortality
  • In many antiarrhythmic drug trials for non-life-threatening arrhythmias, active drug treatment was associated with increased mortality.
  • Risk of antiarrhythmic drug therapy probably is greatest in patients with structural heart disease.
  • Pooled analysis of data from several randomized, controlled studies in patients with atrial flutter and fibrillation indicates that quinidine therapy may be associated with a mortality rate 3 times higher compared with that associated with placebo; consider the increased risk of death when initiating quinidine therapy.
  • Pooled analysis of clinical trials showed mortality with quinidine for non-life-threatening ventricular arrhythmias as consistently exceeding that associated with various alternative antiarrhythmic drugs (i.e., flecainide, mexiletine, propafenone, tocainide).
  • Excessive mortality or nonfatal cardiac arrest rate (7.7%) in encainide- or flecainide-treated patients with asymptomatic non-life-threatening ventricular arrhythmias (with MI history >6 days but <2 years) in NHLBI's long-term CAST study relative to placebo.
  • Applicability of CAST findings to other populations (e.g., those without recent MI) uncertain.

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quinidine
(KWIN i deen)
MP 124 | 300 mgMP 124   300 mg
bottle, 100 each Quinidine SO4 300mg, Oral tablet, white, round-shaped, scored, side 1:MP 124
MP 108 | 200 mgMP 108   200 mg
bottle, 100 each Quinidine SO4 200mg, Oral tablet, white, round-shaped, scored, side 1:MP 108
5454 / DAN DAN | 300 mg5454 / DAN DAN   300 mg
bottle, 100 each Quinidine SO4 300mg, Oral tablet, white, round-shaped, scored, side 1:5454, side 2:DAN DAN
E 512 | 300 mgE 512   300 mg
bottle, 100 each Quinidine SO4 300mg, Oral tablet, white, round-shaped, scored, side 1:E 512
MP 108 | 200 mgMP 108   200 mg
bottle, 100 each Quinidine SO4 200mg, Oral tablet, white, round-shaped, scored, side 1:MP 108
5438 / DAN DAN | 200 mg5438 / DAN DAN   200 mg
bottle, 100 each Quinidine SO4 200mg, Oral tablet, white, round-shaped, scored, side 1:5438, side 2:DAN DAN
MP 124 | 300 mgMP 124   300 mg
bottle, 100 each Quinidine SO4 300mg, Oral tablet, white, round-shaped, scored, side 1:MP 124
DAN DAN / 5454 | 300 mgDAN DAN / 5454   300 mg
bottle, 100 each Quinidine SO4 300mg, Oral tablet, white, round-shaped, scored, side 1:DAN DAN, side 2:5454
E 511 | 200 mgE 511   200 mg
bottle, 100 each Quinidine SO4 200mg, Oral tablet, white, round-shaped, scored, side 1:E 511
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