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pyridostigmine Images

Generic Name: pyridostigmine

Brand Names: Mestinon, Mestinon Timespan

There is an FDA Alert for this drug. Click here to view it.

    Military Use for Soman Poisoning Prophylaxis
  • Use of pyridostigmine alone is not protective against soman effects. Efficacy depends on rapid use of nerve agent antidotes (i.e., atropine and pralidoxime) following nerve agent exposure.
  • Protective garments (e.g., masks, hoods, overgarments) specifically designed for protection from chemical nerve agents are the primary means of protection against nerve agent exposure; do not rely solely on pretreatment with pyridostigmine, atropine, and pralidoxime to provide complete protection.
  • Do not administer pyridostigmine after soman exposure. Discontinue at first sign of nerve agent poisoning; may exacerbate effects of a sublethal exposure.

    Experience of Health Care Personnel
  • Pyridostigmine should be administered by IV injection only by adequately trained individuals familiar with the drug’s actions, characteristics, and risks.

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