IV Administration Rate
- Must be administered IV slowly.
- Do not exceed 50 mg/minute in adults.
- Do not exceed 1–3 mg/kg per minute in pediatric patients.
REMS:
FDA approved a REMS for phenytoin to ensure that the benefits of a drug outweigh the risks. However, FDA later rescinded REMS requirements. See the FDA REMS page ([Web]) or the ASHP REMS Resource Center ([Web]).