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oxandrolone Images

Generic Name: oxandrolone

Brand Names: Oxandrin

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    Peliosis Hepatis
  • Peliosis hepatis, a condition in which the liver contains blood-filled cysts, reported with androgen therapy. May present with minimal hepatic dysfunction, or effects may not be apparent until complicated by life-threatening liver failure or rupture of the cysts resulting in intra-abdominal hemorrhage. (See Hepatic Effects under Cautions.)
  • Discontinuance of androgen therapy usually results in resolution of liver lesions.

    Hepatic Adenoma and Carcinoma
  • Liver cell tumors reported with androgen therapy. Tumors are usually benign and androgen dependent; hepatocellular carcinoma, sometimes fatal, also reported.
  • Liver cell tumors associated with androgens are more vascular than other hepatic tumors; hepatic effects may not be apparent until complicated by life-threatening intra-abdominal hemorrhage.
  • Discontinuance of androgen therapy often but not always results in regression or cessation of progression of the tumor.

    Lipid Abnormalities
  • May markedly alter serum lipoprotein concentrations; decreased HDL- and increased LDL-cholesterol reported with androgen therapy. Consider increased risk of cardiovascular disease (e.g., atherosclerosis and CAD). (See Lipid Abnormalities under Cautions.)

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