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metformin Images

Generic Name: metformin

Brand Names: Metformin Hydrochloride ER, Glumetza, Riomet, Glucophage XR, Glucophage, Fortamet

There is an FDA Alert for this drug. Click here to view it.

  • Lactic acidosis rare but potentially fatal. Increased risk of lactic acidosis in patients with renal impairment, advanced age, metformin plasma concentrations >5 mcg/mL.
  • Generally has occurred in diabetic patients with severe renal insufficiency who frequently had concomitant medical and/or surgical problems and were receiving multiple drugs.
  • Periodically monitor renal function and use the minimum effective dosage. Withhold promptly in patients with any condition associated with hypoxemia, sepsis, or dehydration. Avoid use in patients with clinical or laboratory evidence of hepatic impairment. Discontinue therapy temporarily in patients undergoing surgery or receiving parenteral iodinated radiographic contrast media. Drugs that may affect renal function or alter metformin elimination should be used with caution.
  • Advise patients not to consume excessive amounts of alcohol.
  • If lactic acidosis occurs, discontinue metformin. Immediate hospitalization and treatment required.

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