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Ketorolac Tromethamine Nasal spray, solution

It is used for a short while to treat moderate to severe pain, including pain after surgery

Generic Name: ketorolac

Brand Names: Toradol, Ketorolac Tromethamine

There is an FDA Alert for this drug. Click here to view it.

What is this medicine?

KETOROLAC (kee toe ROLE ak) is a non-steroidal anti-inflammatory drug (NSAID). It is used for a short while to treat moderate to severe pain, including pain after surgery. It should not be used for more than 5 days.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • bleeding disorders
  • cigarette smoker
  • drink more than 3 alcohol-containing drinks a day
  • heart disease
  • high blood pressure
  • history of stomach bleeding
  • kidney disease
  • liver disease
  • lung or breathing disease, like asthma
  • stomach or intestine problems
  • an unusual or allergic reaction to ketorolac, aspirin, other NSAIDs, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for use in the nose. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take it more often than directed.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • aspirin and aspirin-like medicines
  • cidofovir
  • methotrexate
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • pemetrexed
  • pentoxifylline
  • probenecid

This medicine may also interact with the following medications:

  • alcohol
  • alendronate
  • alprazolam
  • carbamazepine
  • certain medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin
  • diuretics
  • flavocoxid
  • fluoxetine
  • garlic
  • ginger
  • ginkgo
  • lithium
  • medicines for blood pressure
  • muscle relaxants
  • phenytoin
  • thiothixene

What should I watch for while using this medicine?

Tell your doctor or health care professional if your pain does not go away, if it gets worse, or if you have new or a different type of pain.

Do not take other medicines that contain aspirin, ibuprofen, or naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many medicines available without a prescription should not be taken with this medicine.

This medicine does not prevent heart attack or stroke. In fact, this medicine may increase the chance of a heart attack or stroke. The chance may increase with longer use of this medicine and in people who have heart disease. If you take aspirin to prevent heart attack or stroke, talk with your doctor or health care professional.

This medicine can cause ulcers and bleeding in the stomach and intestines at any time during treatment. This can happen with no warning and may cause death. There is increased risk with taking this medicine for a long time. Smoking, drinking alcohol, older age, and poor health can also increase risks. Call your doctor right away if you have stomach pain or blood in your vomit or stool.


Last Updated: May 18, 2011
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