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Drug Notebook

FDA Alerts

  • Clinical toxicity of oral and IV ganciclovir includes granulocytopenia, anemia, and thrombocytopenia.
  • In animal studies, ganciclovir was carcinogenic, teratogenic, and caused aspermatogenesis.
  • The only FDA-approved indications for IV ganciclovir are treatment of CMV retinitis in immunocompromised patients and prevention of CMV disease in transplant recipients at risk.
  • The only FDA-approved indications for oral ganciclovir are prevention of CMV disease in patients with advanced HIV infection, maintenance treatment of CMV retinitis in immunocompromised patients, and prevention of CMV disease in solid organ transplant recipients.
  • Because oral ganciclovir is associated with a risk of more rapid progression of CMV retinitis, it should be used as maintenance treatment only in those for whom this risk is balanced by the benefits associated with avoiding daily IV infusions.

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ganciclovir
(gan SYE kloe veer)
CYTOVENE 250mg ROCHE | 250 mgCYTOVENE 250mg ROCHE   250 mg
bottle, 180 each Ganciclovir 250mg, Oral capsule, green, blue-banded, oblong-shaped, side 1:CYTOVENE 250mg ROCHE
CYTOVENE 500mg ROCHE | 500 mgCYTOVENE 500mg ROCHE   500 mg
bottle, 180 each Ganciclovir 500mg, Oral capsule, green, yellow, blue-banded, oblong-shaped, side 1:CYTOVENE 500mg ROCHE
RX636 RX636 | 250 mgRX636 RX636   250 mg
bottle, 180 each Ganciclovir 250mg, Oral capsule, green, opaque, oblong-shaped, side 1:RX636 RX636
RX637 RX637 | 500 mgRX637 RX637   500 mg
bottle, 180 each Ganciclovir 500mg, Oral capsule, green, opaque, yellow, oblong-shaped, side 1:RX637 RX637
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