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Drug Notebook

FDA Alerts

    Hepatotoxicity
  • Severe liver injury (i.e., increased serum transaminase concentrations, jaundice, hepatic encephalopathy, acute hepatic failure) reported, sometimes resulting in hospitalization and/or rarely death; manifestations generally occurred within first 3 months and in some patients, were reversible after discontinuance.
  • Measure serum transaminase concentrations prior to initiation of therapy, monthly during first 4 months, and periodically thereafter.
  • Immediately measure serum transaminase (especially ALT) concentrations if manifestations suggestive of liver dysfunction (e.g., nausea, vomiting, abdominal pain, fatigue, anorexia, flu-like symptoms, hyperbilirubinuria, jaundice, right upper quadrant tenderness) occur.
  • Immediately discontinue if jaundice develops or serum ALT concentration is >2 times ULN; monitor liver function closely until resolves.

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flutamide
(FLOO ta mide)
SCHERING 525 SCHERING 525 | 125 mgSCHERING 525 SCHERING 525   125 mg
box, 100 unit dose blister packs, 1 each Flutamide 125mg, Oral capsule, beige, brown, oblong-shaped, side 1:SCHERING 525 SCHERING 525
LOGO 4960 | 125 mgLOGO 4960   125 mg
bottle, 180 each Flutamide 125mg, Oral capsule, brown, oblong-shaped, side 1:LOGO 4960
93 7120 93 7120 | 125 mg93 7120 93 7120   125 mg
bottle, 500 each Flutamide 125mg, Oral capsule, beige, oblong-shaped, side 1:93 7120 93 7120
barr 870 | 125 mgbarr 870   125 mg
bottle, 30 each Flutamide 125mg, Oral capsule, brown, opaque, white, oblong-shaped, side 1:barr 870
barr 870 | 125 mgbarr 870   125 mg
bottle, 180 each Flutamide 125mg, Oral capsule, brown, opaque, white, oblong-shaped, side 1:barr 870
E 1125 E 1125 | 125 mgE 1125 E 1125   125 mg
bottle, 500 each Flutamide 125mg, Oral capsule, brown, white, oblong-shaped, side 1:E 1125 E 1125
93 7120 93 7120 | 125 mg93 7120 93 7120   125 mg
bottle, 500 each Flutamide 125mg, Oral capsule, beige, opaque, oblong-shaped, side 1:93 7120 93 7120
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