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Drug Notebook

FDA Alerts

  • Estrogens increase the risk of endometrial cancer in postmenopausal women. (See Endometrial Cancer under Cautions.)
  • Do not use estrogens with or without progestins for prevention of cardiovascular disease (see Cardiovascular Risk Reduction under Uses and Cardiovascular Disorders under Cautions) or dementia (see Alzheimer's Disease under Uses).
  • The Women’s Health Initiative (WHI) study of estrogen alone reported increased risks of stroke and DVT in postmenopausal women receiving approximately 7 years of therapy with conjugated estrogens 0.625 mg daily.
  • The WHI study of estrogen plus progestin reported increased risks of MI, stroke, invasive breast cancer, pulmonary embolism, and DVT in postmenopausal women receiving >5 years of therapy with conjugated estrogens 0.625 mg in conjunction with medroxyprogesterone acetate 2.5 mg daily.
  • The WHI Memory Study (WHIMS) reported increased risk of developing probable dementia in postmenopausal women ≥65 years of age receiving long-term therapy (4–5 years) with conjugated estrogens in conjunction with medroxyprogesterone acetate or conjugated estrogen alone. Not known whether this finding also applies to younger postmenopausal women.
  • Other dosages of conjugated estrogens with medroxyprogesterone and other combinations or dosage forms of estrogens with progestin not studied in WHI trials; in absence of comparable data, assume risks are similar.
  • Prescribe estrogens (with or without progestins) at the lowest effective dose and for the shortest duration consistent with treatment goals and risks for the individual woman.

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estradiol
(es tra DYE ole)
WC / 720 1/2 | .5 mgWC / 720 1/2   .5 mg
bottle, 100 each Estradiol 0.5mg, Oral tablet, white, oval-shaped, scored, side 1:WC, side 2:720 1/2
LOGO 756 | 2 mgLOGO 756   2 mg
bottle, 100 each Estradiol 2mg, Oral tablet, green, round-shaped, scored, side 1:LOGO 756
WC / 721 1 | 1 mgWC / 721 1   1 mg
bottle, 100 each Estradiol 1mg, Oral tablet, purple, oval-shaped, scored, side 1:WC, side 2:721 1
WC / 722 2 | 2 mgWC / 722 2   2 mg
bottle, 100 each Estradiol 2mg, Oral tablet, green, oval-shaped, scored, side 1:WC, side 2:722 2
WC / 721 1 | 1 mgWC / 721 1   1 mg
bottle, 30 each Estradiol 1mg, Oral tablet, purple, oval-shaped, scored, side 1:WC, side 2:721 1
WC / 722 2 | 2 mgWC / 722 2   2 mg
bottle, 30 each Estradiol 2mg, Oral tablet, green, oval-shaped, scored, side 1:WC, side 2:722 2
LOGO 755 | 1 mgLOGO 755   1 mg
bottle, 100 each Estradiol 1mg, Oral tablet, purple, mottled, round-shaped, scored, side 1:LOGO 755
886 1 / b | 1 mg886 1 / b   1 mg
bottle, 30 each Estradiol 1mg, Oral tablet, purple, oval-shaped, scored, side 1:886 1, side 2:b
E 3 / M | .5 mgE 3 / M   .5 mg
bottle, 100 each Estradiol 0.5mg, Oral tablet, white, round-shaped, scored, side 1:E 3, side 2:M
E 5 / M | 2 mgE 5 / M   2 mg
bottle, 100 each Estradiol 2mg, Oral tablet, blue, round-shaped, scored, side 1:E 5, side 2:M
899 1/2 / b | .5 mg899 1/2 / b   .5 mg
bottle, 100 each Estradiol 0.5mg, Oral tablet, white, oval-shaped, scored, side 1:899 1/2, side 2:b
887 2 / b | 2 mg887 2 / b   2 mg
bottle, 30 each Estradiol 2mg, Oral tablet, green, oval-shaped, scored, side 1:887 2, side 2:b
WATSON 528 | .5 mgWATSON 528   .5 mg
bottle, 100 each Estradiol 0.5mg, Oral tablet, white, round-shaped, scored, side 1:WATSON 528
WATSON 488 | 2 mgWATSON 488   2 mg
bottle, 100 each Estradiol 2mg, Oral tablet, green, round-shaped, scored, side 1:WATSON 488
AP 026 | 1 mgAP 026   1 mg
bottle, 100 each Estradiol 1mg, Oral tablet, purple, round-shaped, scored, side 1:AP 026
AP 025 | .5 mgAP 025   .5 mg
bottle, 100 each Estradiol 0.5mg, Oral tablet, white, round-shaped, scored, side 1:AP 025
WATSON 528 | .5 mgWATSON 528   .5 mg
bottle, 100 each Estradiol 0.5mg, Oral tablet, white, round-shaped, scored, side 1:WATSON 528
AP 027 | 2 mgAP 027   2 mg
bottle, 100 each Estradiol 2mg, Oral tablet, green, round-shaped, scored, side 1:AP 027
E 4 / M | 1 mgE 4 / M   1 mg
bottle, 100 each Estradiol 1mg, Oral tablet, peach, round-shaped, scored, side 1:E 4, side 2:M
WATSON 487 | 1 mgWATSON 487   1 mg
bottle, 100 each Estradiol 1mg, Oral tablet, gray, round-shaped, scored, side 1:WATSON 487
WC 391 / LOGO | 1.8 mgWC 391 / LOGO   1.8 mg
bottle, 100 each Estradiol Acetate 1.8mg, Oral tablet, yellow, round-shaped, side 1:WC 391, side 2:LOGO
WC 390 / LOGO | .9 mgWC 390 / LOGO   .9 mg
bottle, 100 each Estradiol Acetate 0.9mg, Oral tablet, white, round-shaped, side 1:WC 390, side 2:LOGO
WC 389 / Logo | .45 mgWC 389 / Logo   .45 mg
bottle, 100 each Estradiol Acetate 0.45mg, Oral tablet, beige, round-shaped, side 1:WC 389, side 2:Logo
1259 / LOGO | 1 mg1259 / LOGO   1 mg
bottle, 30 each Estradiol 1mg, Oral tablet, red, round-shaped, scored, side 1:1259, side 2:LOGO
0768 / LOGO | .5 mg0768 / LOGO   .5 mg
bottle, 100 each Estradiol 0.5mg, Oral tablet, purple, round-shaped, scored, side 1:0768, side 2:LOGO
1259 / LOGO | 1 mg1259 / LOGO   1 mg
bottle, 100 each Estradiol 1mg, Oral tablet, pink, round-shaped, scored, side 1:1259, side 2:LOGO
0158 / LOGO | 1.5 mg0158 / LOGO   1.5 mg
bottle, 30 each Estradiol 1.5mg, Oral tablet, green, round-shaped, scored, side 1:0158, side 2:LOGO
0748 / LOGO | 2 mg0748 / LOGO   2 mg
bottle, 100 each Estradiol 2mg, Oral tablet, blue, round-shaped, scored, side 1:0748, side 2:LOGO
0748 / LOGO | 2 mg0748 / LOGO   2 mg
bottle, 30 each Estradiol 2mg, Oral tablet, blue, round-shaped, scored, side 1:0748, side 2:LOGO
0158 / LOGO | 1.5 mg0158 / LOGO   1.5 mg
bottle, 100 each Estradiol 1.5mg, Oral tablet, green, round-shaped, scored, side 1:0158, side 2:LOGO
0768 / LOGO | .5 mg0768 / LOGO   .5 mg
bottle, 30 each Estradiol 0.5mg, Oral tablet, purple, round-shaped, scored, side 1:0768, side 2:LOGO
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