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disopyramide Images

Generic Name: disopyramide

Brand Names: Norpace, Disopyramide CR, Norpace CR

There is an FDA Alert for this drug. Click here to view it.

    Mortality
  • Excessive mortality or nonfatal cardiac arrest rate (7.7%) in encainide- or flecainide-treated patients with asymptomatic non-life-threatening ventricular arrhythmias (with MI history >6 days but <2 years) in NHLBI’s long-term CAST study relative to placebo. (See Mortality under Cautions.)
  • Applicability of CAST findings to other populations (e.g., those without recent MI) uncertain.
  • Because of disopyramide’s proarrhythmic properties and lack of evidence of improved survival for any antiarrhythmic drug, reserve disopyramide for life-threatening ventricular arrhythmias.

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