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didanosine Images

Generic Name: didanosine

Brand Names: Videx, Videx Ec

There is an FDA Alert for this drug. Click here to view it.

  • Fatal and nonfatal pancreatitis reported. Temporarily interrupt didanosine therapy in patients with suspected pancreatitis; discontinue in patients with confirmed pancreatitis. (See Pancreatitis under Cautions.)
  • Lactic acidosis and severe hepatomegaly with steatosis (including some fatalities) reported rarely in patients receiving nucleoside reverse transcriptase inhibitors (NRTIs) alone or in conjunction with other antiretrovirals. (See Lactic Acidosis and Severe Hepatomegaly with Steatosis under Cautions.)
  • Fatal lactic acidosis reported in pregnant women receiving didanosine and stavudine with other antiretrovirals. Didanosine in conjunction with stavudine should be used with caution in pregnant women and only if potential benefits outweigh potential risks. (See Pregnancy under Cautions.)


FDA approved a REMS for didanosine to ensure that the benefits of a drug outweigh the risks. However, FDA later rescinded REMS requirements. See the FDA REMS page ([Web]) or the ASHP REMS Resource Center ([Web]).

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