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Drug Notebook

FDA Alerts

    Hepatic Effects of Oral Dantrolene
  • Risk of developing potentially fatal, hepatic injury (e.g., hepatitis); should not be used for unlabeled indications.
  • Females, patients >35 years of age, and those receiving other drugs (especially estrogens) concomitantly are at greatest risk.
  • Risk of symptomatic hepatitis (fatal and nonfatal) may be dose dependent; incidence much higher at dosages ≥800 mg daily than at dosages ≤400 mg daily. Even intermittent, short courses at higher dosages associated with increased risk. Use lowest possible effective dose.
  • Overt hepatitis most frequently observed between 3rd and 12th month of therapy.
  • Frequently monitor hepatic function. (See Hepatic Effects under Cautions.)
  • If benefits are not evident within 45 days, discontinue therapy.

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dantrolene
(DAN troe leen)
DANTRIUM 100mg 0149 0033 | 100 mgDANTRIUM 100mg 0149 0033   100 mg
bottle, 100 each Dantrolene Sod 100mg, Oral capsule, brown, orange, oblong-shaped, side 1:DANTRIUM 100mg 0149 0033
DANTRIUM 25mg 0149 0030 | 25 mgDANTRIUM 25mg 0149 0030   25 mg
bottle, 100 each Dantrolene Sod 25mg, Oral capsule, brown, orange, oblong-shaped, side 1:DANTRIUM 25mg 0149 0030
DANTRIUM 50mg 0149 0031 | 50 mgDANTRIUM 50mg 0149 0031   50 mg
bottle, 100 each Dantrolene Sod 50mg, Oral capsule, brown, orange, oblong-shaped, side 1:DANTRIUM 50mg 0149 0031
DANTRIUM 50mg 0149 0031 | 50 mgDANTRIUM 50mg 0149 0031   50 mg
bottle, 100 each Dantrolene Sod 50mg, Oral capsule, opaque, orange, tan, oblong-shaped, side 1:DANTRIUM 50mg 0149 0031
DANTRIUM 100mg 0149 0033 | 100 mgDANTRIUM 100mg 0149 0033   100 mg
bottle, 100 each Dantrolene Sod 100mg, Oral capsule, opaque, orange, tan, oblong-shaped, side 1:DANTRIUM 100mg 0149 0033
DANTRIUM 50mg 0149 0031 | 50 mgDANTRIUM 50mg 0149 0031   50 mg
bottle, 100 each Dantrolene Sod 50mg, Oral capsule, opaque, orange, tan, oblong-shaped, side 1:DANTRIUM 50mg 0149 0031
DANTRIUM 25mg 0149 0030 | 25 mgDANTRIUM 25mg 0149 0030   25 mg
bottle, 100 each Dantrolene Sod 25mg, Oral capsule, opaque, orange, tan, oblong-shaped, side 1:DANTRIUM 25mg 0149 0030
G443 G443 | 100 mgG443 G443   100 mg
bottle, 100 each Dantrolene Sod 100mg, Oral capsule, red-orange, yellow, oblong-shaped, side 1:G443 G443
G441 G441 | 25 mgG441 G441   25 mg
bottle, 100 each Dantrolene Sod 25mg, Oral capsule, green, yellow, oblong-shaped, side 1:G441 G441
G442 G442 | 50 mgG442 G442   50 mg
bottle, 100 each Dantrolene Sod 50mg, Oral capsule, blue, yellow, oblong-shaped, side 1:G442 G442
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