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busulfan Images

Generic Name: busulfan

Brand Names: Busulfex, Myleran

There is an FDA Alert for this drug. Click here to view it.

    Hematologic Toxicity
  • Highly toxic drug with a low therapeutic index.
  • Possible severe bone marrow hypoplasia; discontinue therapy temporarily or reduce dosage at the first sign of abnormal bone marrow depression. In some cases, bone marrow examination may be necessary in addition to blood counts.
    Experience of Supervising Clinician
  • Use under constant supervision of a qualified clinician experienced in therapy with antineoplastic agents.
  • Clinicians supervising the administration of IV busulfan also should be experienced in hematopoietic stem cell transplantation and in the management of patients with severe pancytopenia.

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