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Drug Notebook

FDA Alerts

    Intrathecal Baclofen Withdrawal
  • Abrupt discontinuation of intrathecal baclofen may result in seizures, high fever, altered mental status, exaggerated rebound spasticity, and muscle rigidity; in rare cases, progression to rhabdomyolysis, multisystem organ failure, and death may occur.
  • Give careful attention to programming and monitoring of infusion system, refill scheduling and procedures, and pump alarms to prevent abrupt discontinuance. (See Warnings under Cautions.)
  • Advise patients and caregivers of the importance of keeping scheduled refill visits and of the early signs and symptoms of baclofen withdrawal.
  • Give special attention to patients at apparent risk for withdrawal (e.g., spinal cord injury at T6 level or above, communication difficulties, history of withdrawal symptoms from oral or intrathecal baclofen).

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baclofen
(BAK loe fen)
Z 4097 / 20 | 20 mgZ 4097 / 20   20 mg
bottle, 100 each Baclofen 20mg, Oral tablet, white, round-shaped, notched, side 1:Z 4097, side 2:20
832 BC20 | 20 mg832 BC20   20 mg
bottle, 100 each Baclofen 20mg, Oral tablet, white, round-shaped, scored, side 1:832 BC20
DAN 5731 / 20 | 20 mgDAN 5731 / 20   20 mg
bottle, 100 each Baclofen 20mg, Oral tablet, white, round-shaped, scored, side 1:DAN 5731, side 2:20
10 / DAN 5730 | 10 mg10 / DAN 5730   10 mg
bottle, 100 each Baclofen 10mg, Oral tablet, white, round-shaped, scored, side 1:10, side 2:DAN 5730
BAC 10 / 832 | 10 mgBAC 10 / 832   10 mg
bottle, 100 each Baclofen 10mg, Oral tablet, white, round-shaped, scored, side 1:BAC 10, side 2:832
Z 4096 / 10 | 10 mgZ 4096 / 10   10 mg
bottle, 100 each Baclofen 10mg, Oral tablet, white, round-shaped, notched, side 1:Z 4096, side 2:10
10 / DAN 5730 | 10 mg10 / DAN 5730   10 mg
bottle, 30 each Baclofen 10mg, Oral tablet, white, round-shaped, scored, side 1:10, side 2:DAN 5730
V / 22 66 | 20 mgV / 22 66   20 mg
bottle, 30 each Baclofen 20mg, Oral tablet, white, oblong-shaped, scored, side 1:V, side 2:22 66
832 BC20 | 20 mg832 BC20   20 mg
container, 6 Single item blister pack, 30 each Baclofen 20mg, Oral tablet, white, round-shaped, scored, side 1:832 BC20
Z 4096 / 10 | 10 mgZ 4096 / 10   10 mg
box, 10 unit dose strips, 10 each Baclofen 10mg, Oral tablet, white, round-shaped, notched, side 1:Z 4096, side 2:10
BAC 10 / 832 | 10 mgBAC 10 / 832   10 mg
container, 12 Single item blister pack, 30 each Baclofen 10mg, Oral tablet, white, round-shaped, scored, side 1:BAC 10, side 2:832
V / 22 66 | 20 mgV / 22 66   20 mg
bottle, 100 each Baclofen 20mg, Oral tablet, white, oblong-shaped, scored, side 1:V, side 2:22 66
LIORESAL / 10 10 | 10 mgLIORESAL / 10 10   10 mg
bottle, 100 each Baclofen 10mg, Oral tablet, white, oval-shaped, scored, side 1:LIORESAL, side 2:10 10
LIORESAL / 20 20 | 20 mgLIORESAL / 20 20   20 mg
bottle, 100 each Baclofen 20mg, Oral tablet, white, oblong-shaped, scored, side 1:LIORESAL, side 2:20 20
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