Drugs A - Z
Yerba santa (Eriodictyon californicum)
Generic Name: Yerba Santa
CategoryHerbs & Supplements
Consumptive's weed, bear's weed, eriodictyol, Eriodictyon californicum, Eriodictyon glutinosum, gum bush, holy herb, mountain balm, sacred herb, tarweed, Wigandia californicum.
Note: Not to be confused with other herbs which share the same common name(s). For example, the common name "mountain balm" is also used for Ceanothus velutinus, Satureja chandleri, and Calamintha nepeta. The common name "consumptive's weed" is associated with three different Eriodictyon species. The common name "gum bush" is also associated with several different Eriodictyon species. The common name "bear's weed" is also used for Arctostaphylos uva-ursi. The common name "tarweed" is associated with many species of Hemizonia and Madia. The common name "holy herb" is used for marijuana (Cannabis sativa), hyssop (Sorghum vulgare), basil (Ocimum basilicum), verbena (Verbena officinalis) and aloe (Aloe barbadensis). The common name "Sacred herb" is used for marijuana and tobacco (Nicotiana tabacum).
Chumash Indians and other California Indians have used yerba santa (Eriodictyon californicum) and other related species (Eriodictyon crassifolium, Eriodictyon trichocalyx) for many centuries in the treatment of pulmonary (lung) conditions, saliva production, and to stop bleeding of minor cuts and scrapes.
In the United States and Britain, Eriodictyon californicum was formally used for conditions including influenza, bacterial pneumonia, asthma, bronchitis, and tuberculosis starting in the late 1800s until the 1960s (when drug regulations became more stringent around proof of efficacy). Subsequently, the extracts remained GRAS ("generally regarded as safe") as a flavor for foods, beers, and pharmaceuticals (such as to hide the bitterness of quinine). Eriodictyon plant extracts have also been used in cosmetics.
Eriodictyon species contain flavones with free radical scavenging (antioxidant) properties, and have therefore been proposed as being beneficial for a number of health conditions. However, there is little scientific study of yerba santa in humans, and effectiveness has not been demonstrated for any specific condition.
EvidenceDISCLAIMER: These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
Pulmonary conditions (lung conditions):
There is an extensive clinical history of use of Eriodictyon extracts in pulmonary conditions such as influenza, bacterial pneumonia, asthma, bronchitis, and tuberculosis. However, additional study is needed to make a firm recommendation.
TraditionWARNING: DISCLAIMER: The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.
Allergies, antibacterial, antifungal, anti-inflammatory, anti-parasitic, antioxidant, antiviral, arthritis, asthma, blood coagulation disorders, cancer, cosmetics, dry mouth, excipient (inactive ingredient) for drug delivery, food flavoring, hypercholesterolemia (high cholesterol), hypertension (high blood pressure), malaria, saliva production, skin scrapes, smooth muscle relaxant, tuberculosis, urinary tract infections.
Adults (18 years and older):
There is no proven safe or effective dose for yerba santa in adults. Traditionally, 1-2 milliliters of fluid extract has been taken by mouth with a spoon every 3-4 hours for no more than ten days.
Poultices have been made by crushing 0.2 kilograms of the leaves in 1,000 milliliters of water. The leaves have been used traditionally as a treatment for pulmonary (lung) congestion by placing the slightly wet leaves on the chest. The poultice is usually used once or twice every day for up to two weeks.
Children (younger than 18 years):
There is no proven safe or effective dose for yerba santa in children. Traditionally, 1 milliliter of the alcohol extract has been used in children. Caution is warranted in children due to the presence of ethanol. Poultices have also been applied on the skin.
SafetyDISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.
Avoid in individuals with a known allergy or hypersensitivity to Eriodictyon species.
Side Effects and Warnings
There are no published reports of toxicity clearly attributable to yerba santa (Eriodictyon californicum), although this herb has been used for centuries by California Indians with a belief in its safety. However, there are no available scientific evaluations of toxicity or safety.
Pregnancy and Breastfeeding
Interactions with Drugs
The flavonoids homoeriodictyol and eriodictyol found in yerba santa may interfere with the way the body processes certain drugs using the liver's "cytochrome P450" enzyme system. As a result, the levels of these drugs may be increased in the blood, and may cause increased effects or potentially serious adverse reactions. Patients using any medications should check the package insert, and speak with a qualified healthcare professional, including a pharmacist, about possible interactions.
Interactions with Herbs and Dietary Supplements
The flavonoids homoeriodictyol and eriodictyol found in yerba santa may interfere with the way the body processes certain herbs or supplements using the liver's "cytochrome P450" enzyme system. As a result, the levels of other herbs or supplements may become too high in the blood. It may also alter the effects that other herbs or supplements possibly have on the P450 system.
This information is based on a systematic review of scientific literature, and was peer-reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): James David Adams, Jr., PhD (University of Southern California); Ethan Basch, MD (Memorial Sloan-Kettering Cancer Center); Catherine DeFranco Kirkwood, MPH, CCCJS-MAC (MD Anderson Cancer Center); Mary Giles, PharmD (University of Rhode Island); Adrianne Rogers, MD (Boston University School of Medicine); Erica Seamon, PharmD (Nova Southeastern University); Joshua Sklar, PharmD (University of Rhode Island); Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Wendy Weissner, BA (Natural Standard Research Collaboration).
BibliographyDISCLAIMER: Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.