Drugs A - Z

Tylophora (Tylophora indica)

treats Asthma

Generic Name: Tylophora asthmatica

Category

Herbs & Supplements

Synonyms

Anta-mul (Hindi), Indian ipecac, Indian ipecacuahna, Jangli-pikavan, Tylophora asthmatica, Tylophora pubescens, Tylophora vomitoria, Voight, wall.

Background

Tylophora is a climbing perennial plant that grows in India. The leaves of tylophora have been traditionally used for treating asthma, earning the name of Tylophora asthmatica. In folk medicine, it has been used for other respiratory problems such as allergies, bronchitis and the common cold. It is also believed by some to have laxative and other purgative properties. Additionally, it has been employed to treat dysentery and joint pain.

The only available clinical trials done on tylophora test its effectiveness in bronchial asthma. To date, there are no trials available examining its effectiveness in treating other conditions.

The occurrence of adverse events that occur when the leaf of tylophora is taken orally seems to be reduced when the leaves are taken in capsule form instead of chewing.

Evidence

DISCLAIMER: These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.

Asthma: Available studies of tylophora for asthma show conflicting results and therefore efficacy remains unproven.
Grade: C

Tradition

WARNING: DISCLAIMER: The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.
Adrenal support, allergies, antispasmodic, bronchitis, colds, dermatitis, diaphoretic, dysentery, expectorant, inflammation, joint pain, laxative, rheumatism.

Dosing

Adults (over 18 years old)

There is no proven effective dose for tylophora. Traditionally, doses of 250 milligrams 1-3 times daily, standardized to 0.1% of tylophorine per dose, and doses of 30-60 milligrams twice daily standardized to 0.15% of tylophorine have been used. One clinical trial reports using 350 milligrams of tylophora leaf placed in a capsule and given once daily for seven days. Some experts have used tylophora leaf taken in the amount of 200-400 milligrams dried herb daily. A clinical trial reports the use of one tylophora leaf taken orally daily in the morning for six days. One clinical trial reports the use of 40mg of alcoholic extract of Tylophora indica daily for six days.

There are reports using 400-500 milligrams of alkaloid tylophora in powder form given once daily to asthmatic patients for six days. Another trial used one leaf of tylophora daily for up to 12 days in asthmatic patients.

Children (under 18 years old)

There is no proven effective dose for tylophora in children.

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