Drugs A - Z

Salvia divinorum

Generic Name: Salvia divinorum

Category

Herbs & Supplements

Synonyms

Diviner's mint, diviner's sage, hardwickiic acid, hierba Maria (Spanish), hojas de la pastora (Spanish), hojas de Maria pastora (Spanish), la hembra (Spanish), la Maria (Spanish), Lamiaceae (family), loliolide, magic mint, María pastora, Mexican mint, mint plant, neoclerodane diterpene, neoclerodane diterpenoids, presqualene alcohol, sage of the seers, Sally-D, salvia, salvinorinyl-2-heptanoate, shepherdess's herb, ska Maria pastora (Mazatec), ska pastora (Mazatec), the female, yerba de Maria (Spanish), yerba Maria (Spanish).

Background

Salvia (Salvia divinorum) is a hallucinogenic plant that is traditionally used by the Mazatec culture in central Mexico. It is grown in California and other parts of the United States where it is used as a legal hallucinogen and is becoming popular with teenagers and young adults. Laws in Finland, Denmark, and Australia prohibit cultivating, consuming, or dealing with salvia.

Most studies have investigated salvia's active constituent, salvinorin A. Currently, there are no high-quality trials investigating salvia's therapeutic uses. Animal studies of salvia have not shown any toxicity even at high doses, but use of salvia can cause central nervous system (CNS) and psychiatric effects due to its hallucinogenic properties. Some researchers believe that salvinorin A may show promise as a psychotherapeutic compound for diseases manifested by perceptual distortions (e.g. schizophrenia, dementia, and bipolar disorders).

Evidence

DISCLAIMER: These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.

Tradition

WARNING: DISCLAIMER: The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.
Alzheimer's disease, bipolar disorder, cardiovascular disease, dementia, depression, diarrhea, drug abuse (stimulant), gastrointestinal motility, hallucinogenic, pain, pruritus (severe itching), schizophrenia.

Dosing

Adults (over 18 years old)

There is no proven safe or effective dose for salvia in adults.

Children (under 18 years old)

There is no proven safe or recommended dose for salvia in children.

Safety

DISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.

Allergies

Avoid in individuals with a known allergy or hypersensitivity to salvia.

Side Effects and Warnings

Salvia may cause decreased heart rate, increased perspiration, changes in body temperature, chills, inability to control muscles, inability to maintain balance, loss of coordination, and short-term effects on motor-control. The effects of salvia are typically short-lived.

Salvia may induce hallucinations and psychedelic-like changes in visual perception and mood. Visual hallucinations may include perception of bright lights and vivid colors and shapes, as well as body movements and body or object distortions.

Dizziness, slurred speech, nausea, awkward sentence patterns, and general change in consciousness have been reported.

Use cautiously in patients with psychiatric disorders, including depression, due to salvia's ability to induce hallucinations and other mood changes.

Pregnancy & Breastfeeding

Salvia is not recommended in pregnant or breastfeeding women due to a lack of available scientific evidence.

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