Drugs A - Z

Saiboku-to

Generic Name: licorice

Category

Herbs & Supplements

SYNONYMS

Asian ginseng, Asian skullcap, ginger, herbal remedies, hoelen, jujube, Kampo, licorice, magnolia, minor bupleurum decoction, perilla, pinellia, TJ-96, ziao-chai-hu-tang.

BACKGROUND

Saiboku-to is a Japanese herbal formula that is commonly used to treat asthma. Saiboku-to has been approved by the Japanese Health Ministry for the treatment of asthma. Saiboku-to has shown to decrease asthmatic inflammation in numerous trials as compared to placebo.

Saiboku-to contains bupleurum, hoelen, pinellia, magnolia, Asian ginseng, Asian skullcap, licorice, perilla, ginger and jujube. The combination of herbs is thought to have significant anti-inflammatory and anti-histamine effects.

THEORY/EVIDENCE

Saiboku-to has been approved by the Japanese Health Ministry for the treatment of asthma. Saiboku-to has shown to decrease asthmatic inflammation in numerous trials as compared to placebo. One trial found that saiboku-to affected platelet-activating factor. The platelet-activating factor (PAF) is a chemical mediator responsible for allergic and inflammatory responses. This study showed that patients who took this herb had significant decreases in the asthmatic inflammation they had previously suffered from. This suggests a possible mechanism of action for the herb.

There are also reports of saiboku-to being used for bronchitis, however, there is little evidence suggesting saiboku-to suggest any anti-infective properties.

SAFETY

Taking saiboku-to and steroids together may increase the effects of steroids. This interaction was reported with the concurrent use of prednisolone and siaboku-to. Speak with a qualified healthcare provider before making any decision regarding herbal supplements.

AUTHOR INFORMATION

This information has been edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com).

BIBLIOGRAPHY

Health Encyclopedia. 10 May 2006. http://healthlibrary.epnet.com/GetContent.aspx?token=e0498803-7f62-4563-8d47-5fe33da65dd4&chunkiid=37410

Health Information Library. Asthma. 10 May 2006 http://checksutterfirst.org/health/healthinfo/index.cfm?section=healthinfo&page=article&sgml_id=hn-1012000

Nakamura T, Kuriyama M, Kosuge E, et al. Effects of saiboku-to (TJ-96) on the production of platelet-activating factor in human neutrophils. Ann N Y Acad Sci. 1993 Jun 23;685:572-9.

Saiboku-to. 11 May 2006. http://www.luhs.org/HEALTH/kbase/htm/mdx-/amci/0032/mdx-amci0032.htm

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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