Drugs A - Z

Bromelain

treats Rheumatoid arthritis, Urinary tract infection, Osteoarthritis, Rash, Burn debridement, Nutrit... more

Generic Name: Pineapple bromelain

Category

Herbs & Supplements

Synonyms

Ananas comosus, Ananas sativus, Ananase®, Bromelain-POS, bromeline (pleural), Bromelainum, Bromeliaceae (family), Bromelin, Bromelins, Debridase, Phlogenzym (rutoside, bromelain, and trypsin), enzyme-rutosid combination, ERC (rutosid, bromelain, trypsin), plant protease concentrate, pineapple, pineapple extract, rutosid, Traumanase®, trypsin.

Background

Classified as an herb, bromelain is a sulfur-containing proteolytic digestive enzyme that is extracted from the stem and the fruit of the pineapple plant (Ananas comosus, family Bromeliaceae).

When taken with meals, bromelain is believed to assist in the digestion of proteins. When taken on an empty stomach, it is believed to act medicinally as an anti-inflammatory agent.

The expert panel, the German Commission E, approved bromelain for the treatment of swelling/inflammation of the nose and sinuses caused by injuries and surgery in 1993.

Evidence

DISCLAIMER: These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.

Inflammation: Several preliminary studies suggest that when taken by mouth, bromelain can reduce inflammation or pain caused by inflammation. Better quality studies are needed to confirm these results.
Grade: B

Sinusitis (sinus inflammation): It is proposed that bromelain may be a useful addition to other therapies used for sinusitis (such as antibiotics) due to its ability to reduce inflammation/swelling. Studies report mixed results, although overall bromelain appears to be beneficial for reducing swelling and improving breathing. Better studies are needed before a strong recommendation can be made.
Grade: B

Burn debridement: A bromelain-derived debriding agent, Debridase, has been studied on deep second degree and third degree burns with positive results. Further results are needed to confirm these results.
Grade: C

Cancer: There is not enough information to recommend for or against the use of bromelain in the treatment of cancer, either alone or in addition to other therapies.
Grade: C

Chronic obstructive pulmonary disease (COPD): There is not enough information to recommend for or against the use of bromelain in COPD.
Grade: C

Digestive enzyme/pancreatic insufficiency: Bromelain is an enzyme with the ability to digest proteins. However, there is little reliable scientific research on whether bromelain is helpful as a digestive aid. Better study is needed before a firm conclusion can be made.
Grade: C

Nutrition supplementation: There is not enough information to recommend for or against the use of bromelain as a nutritional supplement.
Grade: C

Osteoarthritis: There is conflicting evidence on the effectiveness of bromelain to treat osteoarthritis. Further well-designed clinical trials of bromelain alone are needed to confirm these results.
Grade: C

Rash: Bromelain may help treat this type of skin rash. This treatment may be effective because bromelain has been shown to decrease inflammation, regulate the immune system, and have antiviral effects.
Grade: C

Rheumatoid arthritis (RA): There is not enough information to recommend for or against the use of bromelain in rheumatoid arthritis (RA).
Grade: C

Steatorrhea (fatty stools due to poor digestion): There is not enough information to recommend for or against the use of bromelain in the treatment of steatorrhea.
Grade: C

Urinary tract infection (UTI): There is not enough information to recommend for or against the use of bromelain in urinary tract infections.
Grade: C

Licensed from
The Healthline Site, its content, such as text, graphics, images, search results, HealthMaps, Trust Marks, and other material contained on the Healthline Site ("Content"), its services, and any information or material posted on the Healthline Site by third parties are provided for informational purposes only. None of the foregoing is a substitute for professional medical advice, examination, diagnosis, or treatment. Always seek the advice of a physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on the Healthline Site. If you think you may have a medical emergency, call your doctor or 911 immediately. Please read the Terms of Service for more information regarding use of the Healthline Site.
Advertisement