Drugs A - Z
Amaranth oil (Amaranthus L.)
Generic Name: Lipids
CategoryHerbs & Supplements
Achis, achita, African amaranth, African spinach, alegra, amarante, amaranth grain, amaranth hybrid, amaranth seed oil, amaranth tender, Amaranthaceae (family), amaranthoideae, Amaranthus acanthochiton, Amaranthus acutilobius, Amaranthus albus, Amaranthus arenicola, Amaranthus australis, Amaranthus bigelovii, Amaranthus blitoides, Amaranthus blitum, Amaranthus brownie, Amaranthus californicus, Amaranthus cannabinus, Amaranthus caudatus, Amaranthus chihuahuensis, Amaranthus chlorostachys, Amaranthus crassipes, Amaranthus crispus, Amaranthus cruentus, Amaranthus deflexus, Amaranthus dubius, Amaranthus edulis, Amaranthus fimbriatus, Amaranthus floridanus, Amaranthus gangeticus, Amaranthus graecizans, Amaranthus greggii, Amaranthus hybridus, Amaranthus hypochondriacus, Amaranthus leucocarpus, Amaranthus lineatus, Amaranthus lividus, Amaranthus mantegazzianus, Amaranthus minimus, Amaranthus muricatus, Amaranthus obcordatus, Amaranthus palmeri, Amaranthus paniculus, Amaranthus polygonoides, Amaranthus powelii, Amaranthus pringlei, Amaranthus pumilus, Amaranthus quitensis, Amaranthus retroflexus, Amaranthus rudis, Amaranthus scleropoides, Amaranthus spinosus, Amaranthus standleyanus, Amaranthus thunbergii, Amaranthus torreyi, Amaranthus tricolor, Amaranthus tuberculatus, Amaranthus viridis, Amaranthus watsonii, Amaranthus wrightii, amaranto, amarantos, arowo jeta, ataco, Australian amaranth, azorubin, bayam, bayam bhaji, bayam hedjo, bigelow's amaranth, biteku teku, bledos, blero spinach, bondue, bone-bract amaranth, brown's amaranth, buautli, bush greens, calaloo, calalu, California amaranth, California pigweed, callaloo, careless weed, chihuahuan amaranth, Chinese spinach, choito, coimicoyo, common amaranth, common waterhemp, crispleaf amaranth, cuime, efo tete, elephant head amaranth, Florida amaranth, foxtail amaranth, fringed amaranth, fringed pigweed, fuchsschwanz, golden grain of the Gods, green amaranth, greenstripe, Gregg's amaranth, guegui, hinn choy, huautli, Indian spinach, Joseph's-coat, khada sag, kiwicha, komo, kulitis, lady bleeding, large-fruit amaranth, lenga lenga, linoleic acid, livid amaranth, love-lies-bleeding, lovely bleeding, mat amaranth, mchicha, Mexican grain amaranth, millmi, mystical grains of the Aztecs, oleic acid, pale-seeded amaranth, palmer pigweed, Palmer's amaranth, palmitric acid, pendant amaranth, pigweed amaranth, pilewort, Powell amaranth, Powell pigweed, prickly amaranth, Prince-of-Wales-feather, Prince's feather, princess feather, Pringle's amaranth, prostrate amaranth, prostrate pigweed, purple amaranth, quilete, quinoa de castilla, quintonil, ramdana, red amaranth, red cockscomb, red-root amaranth, redroot pigweed, Reuzen amaranth, rough-fruit amaranth, sandhill amaranth, sangorache, seaside amaranth, sharp-lobe amaranth, slender amaranth, smooth amaranth, smooth pigweed, southern amaranth, spinach grass, spiny amaranth, spleen amaranth, spreading amaranth, squalene, stearic acid, super grain of the Aztecs, surinam spinach, tall amaranth, tall waterhemp, tampala, tassel flower, thorny amaranth, thotakura, Thunberg's amaranth, tidal-marsh amaranth, Torrey's amaranth, Trans-Pecos amaranth, tropical amaranth, tumble pigweed, tumbleweed, vegetable amaranth, velvet flower, vitamin E, Watson's amaranth, white pigweed, wild beet, wild blite, Wright's amaranth, yin choi.
Amaranth is grown in Asia and the Americas and harvested primarily for its grain, which is used as a food source for bread, pasta, and infant food.
Amaranth oil has been shown to decrease cholesterol and lipid levels when taken with a low-sodium, heart-healthy diet. However, other studies have shown that amaranth in conjunction with a low-fat diet has no effect on cholesterol levels in patients with high cholesterol. Early research has also shown that amaranth oil may lower blood sugar.
There is not enough scientific evidence of an effect of amaranth for any indication. High-quality research is needed before a recommendation can be made.
EvidenceDISCLAIMER: These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
Amaranth plus a low-sodium, heart-healthy diet decreased cholesterol and blood pressure in patients with heart disease. However, additional evidence is needed before a recommendation can be made in this area.
Immune system function:
Limited evidence suggests that amaranth may stimulate the immune system when combined with a heart-healthy diet in patients with heart disease and high cholesterol. However, additional studies of amaranth alone are needed in this area.
Early research suggests that consuming amaranth greens may improve night blindness. However, more studies are needed before a recommendation can be made.
TraditionWARNING: DISCLAIMER: The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.
Abnormal menstrual bleeding, allergies, antibacterial, antifungal, antiviral, arthritis, asthma, astringent, bed sores, burns, cancer, canker sores, cosmetic uses, diabetes, diarrhea, digestion, diuretic, eczema, energy, high blood pressure, high cholesterol, inflammation, insect bites, leucorrhea (vaginal discharge), lung cancer prevention, nosebleed, nutritional supplement (infant formulas/cereal, pediatric, pre-school children), pain, psoriasis, rash, ulcers, wound care.
Adults (18 years and older)
A tea may be prepared by adding 1 teaspoon of amaranth leaves to 1 cup of cold water and consuming 1 to 2 cups per day. As an antioxidant, 200-400 milligrams of squalene, a constituent of amaranth, has been used daily. To enhance immune function, 600 milligrams of squalene has been used daily. A daily dose of 18 milligrams of amaranth oil has been used for 3 weeks for heart disease. For night vision, a daily dose of 850 micrograms retinol equivalents in the form of amaranth leaves has been used in pregnant women for 6 days per week for 6 weeks.
Children (under 18 years old)
There is no proven safe or effective dose for amaranth in children.
SafetyDISCLAIMER: Many complementary techniques are practiced by healthcare professionals with formal training, in accordance with the standards of national organizations. However, this is not universally the case, and adverse effects are possible. Due to limited research, in some cases only limited safety information is available.
Avoid with allergy or sensitivity to amaranth.
Side Effects and Warnings
There is limited evidence of amaranth's adverse effects. Amaranth may contain high levels of cadmium, nitrates, antitrypsin proteins, and heat-labile factors, which may affect the nervous system. In addition, amaranth grown in nitrogen-rich soil may cause health problems. Amaranth should be used cautiously in those with kidney disorders due to its high oxalate content.
Amaranth may decrease serotonin levels. Amaranth may increase or decrease immune function and should be used with caution in patients with immune disorders or in those taking drugs, herbs, or supplements that affect the immune system.
Amaranth may lower blood sugar levels. Caution is advised in patients with diabetes or hypoglycemia and in those taking drugs, herbs, or supplements that affect blood sugar. Blood glucose levels may need to be monitored by a qualified healthcare professional, and medication adjustments may be necessary.
Amaranth may lower blood pressure. Caution is advised in patients with low blood pressure or in those taking drugs, herbs, or supplements that affect blood pressure. Blood pressure may need to be monitored, and medication adjustments may be necessary.
Pregnancy and Breastfeeding
Interactions with Drugs
Amaranth may lower blood sugar levels. Caution is advised when using medications that may also lower blood sugar. Patients taking drugs for diabetes by mouth or injection should be monitored closely by a qualified healthcare professional. Medication adjustments may be necessary.
Amaranth may lower blood pressure. Caution is advised when using medications that may also lower blood pressure. Blood pressure may need to be monitored, and medication adjustments may be necessary.
Amaranth may interact with antihistamines, agents that affect the immune system, agents that have effects in the eye, and agents that affect the kidney, and may add to the effects of lipid-lowering drugs.
Interactions with Herbs and Dietary Supplements
Amaranth may lower blood sugar levels. Caution is advised when using herbs or supplements that may also lower blood sugar. Blood sugar levels should be monitored closely and medication adjustments may be necessary.
Amaranth may lower blood pressure. Caution is advised when using herbs or supplements that may also lower blood pressure. Blood pressure may need to be monitored, and medication adjustments may be necessary.
Amaranth may interact with antihistamines, probiotics, agents that affect the immune system, agents that have effects in the eye, and agents that affect the kidney. Amaranth may add to the effects of lipid-lowering, fiber-containing, and mineral supplements.
Amaranth may affect the levels of amino acid-containing supplements and some essential fatty acids.
This information is based on a systematic review of scientific literature, and was peer-reviewed and edited by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com): Tracee Abrams, PharmD (University of Rhode Island); Julie Conquer, PhD (RGB Consulting); Dawn Costa, BA, BS (Natural Standard Research Collaboration); Jill M. Grimes Serrano, PhD (Natural Standard Research Collaboration); Jenna Hollenstein, MS, RD, ELS (Natural Standard Research Collaboration); Sarah Taylor, PharmD (University of Pittsburgh); Catherine Ulbricht, PharmD (Massachusetts General Hospital); Minney Varghese, BS (Northeastern University).
BibliographyDISCLAIMER: Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
Chaturvedi A, Sarojini G, Nirmala G, et al. Glycemic index of grain amaranth, wheat and rice in NIDDM subjects. Plant Foods Hum Nutr. 1997;50(2):171-178.
Berger A, Gremaud G, Baumgartner M, et al. Cholesterol-lowering properties of amaranth grain and oil in hamsters. Int J Vitam Nutr Res. 2003;73(1):39-47.
Carlson BC, Jansson AM, Larsson A, et al. The endogenous adjuvant squalene can induce a chronic T-cell-mediated arthritis in rats. Am J Pathol. 2000;156(6):2057-2065.
Culpepper S, Grey T, Vencill W, et al. Glyphosate-resistant Palmer amaranth (Amaranthus palmeri) confirmed in Georgia. Weed Science 2008;620-626.
Gonor KV, Pogozheva AV, Kulakova SN, et al. [The influence of diet with including amaranth oil on lipid metabolism in patients with ischemic heart disease and hyperlipoproteidemia]. Vopr Pitan. 2006;75(3):17-21.
Haskell MJ, Pandey P, Graham JM, et al. Recovery from impaired dark adaptation in nightblind pregnant Nepali women who receive small daily doses of vitamin A as amaranth leaves, carrots, goat liver, vitamin A-fortified rice, or retinyl palmitate. Am J Clin Nutr. 2005;81(2):461-471.
Kim HK, Kim MJ, Cho HY, et al. Antioxidative and anti-diabetic effects of amaranth (Amaranthus esculantus) in streptozotocin-induced diabetic rats. Cell Biochem Funct. 2006;24(3):195-199.
Kim HK, Kim MJ, Shin DH. Improvement of lipid profile by amaranth (Amaranthus esculantus) supplementation in streptozotocin-induced diabetic rats. Ann Nutr Metab 2006;50(3):277-281.
Maier S, Turner N, Lupton J. Serum Lipids in Hypercholesterolemic men and women consuming oat bran and amaranth products. Cereal Chemistry 2000;77(3):297-302.
Martirosyan DM, Miroshnichenko LA, Kulakova SN, et al. Amaranth oil application for coronary heart disease and hypertension. Lipids Health Dis. 2007;6:1.
Negi PS, Roy SK. Changes in beta-carotene and ascorbic acid content of fresh amaranth and fenugreek leaves during storage by low cost technique. Plant Foods Hum Nutr. 2003;58(3):225-230.
Punita A, Chaturvedi A. Effect of feeding crude red palm oil (Elaeis guineensis) and grain amaranth (Amaranthus paniculatus) to hens on total lipids, cholesterol, PUFA levels and acceptability of eggs. Plant Foods Hum Nutr. 2000;55(2):147-157.
Reyes FG, Valim MF, Vercesi AE. Effect of organic synthetic food colours on mitochondrial respiration. Food Addit Contam 1996;13(1):5-11.
Shin DH, Heo HJ, Lee YJ, et al. Amaranth squalene reduces serum and liver lipid levels in rats fed a cholesterol diet. Br J Biomed Sci. 2004;61(1):11-14.
Shukla S, Bhargava A, Chatterjee A, et al. Mineral profile and variability in vegetable amaranth (Amaranthus tricolor). Plant Foods Hum Nutr. 2006;61(1):23-28.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.