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triptorelin
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(trip TOE reh lin)

What is the most important information I should know about triptorelin?

Triptorelin initially causes a temporary increase in serum testosterone levels. Because of this, symptoms of prostate cancer may worsen during the first weeks of treatment. Notify your doctor if you experience new or worsening symptoms such as bone pain; blood in the urine; difficulty urinating; or numbness, tingling, weakness, or paralysis.

What is triptorelin?

Triptorelin reduces the amount of testosterone produced in the body.

Triptorelin is used in the palliative treatment of advanced prostate cancer.

Triptorelin may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before using triptorelin?

Do not use triptorelin without first talking to your doctor if you are allergic to luteinizing hormone releasing hormone (LHRH) or other similar drugs such as leuprolide (Lupron, Viadur, Eligard) or goserelin (Zoladex) . You may not be able to use triptorelin or you may require special monitoring during treatment.

Before using triptorelin, tell your doctor if you have

You may not be able to use triptorelin, or you may require a dosage adjustment or special monitoring during treatment.

Triptorelin is in the FDA pregnancy category X. This means that triptorelin will cause birth defects in an unborn baby. Do not use this medication if you are pregnant or if you could become pregnant during treatment. It is not known whether triptorelin passes into breast milk. Do not use this medication without first talking to your doctor if you are breast-feeding a baby.

How should I use triptorelin?

Triptorelin must be administered under the supervision of a physician.

Triptorelin is injected into the muscle, usually once a month.

Your doctor or nurse will rotate the site of the injection periodically.

Triptorelin initially causes a temporary increase in serum testosterone levels. Because of this, symptoms of prostate cancer may worsen during the first weeks of treatment. Notify your doctor if you experience new or worsening symptoms such as bone pain; blood in the urine; difficulty urinating; or numbness, tingling, weakness, or paralysis.

Triptorelin vials for injection should be stored at room temperature away from moisture and heat.

What happens if I miss a dose?

Contact your doctor if you miss a dose of triptorelin.

What happens if I overdose?

An overdose of triptorelin is unlikely to occur. If you do suspect that an overdose has occurred, contact your doctor, hospital emergency room, or poison control center for advice.

What should I avoid while using triptorelin?

There are no restrictions on food, beverages, or activities while using triptorelin. Follow any special instructions given by your doctor.

What are the possible side effects of triptorelin?

If you experience any of the following serious side effects, stop using triptorelin and seek emergency medical attention or contact your doctor immediately:
  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

  • difficulty urinating or blood in the urine;

  • bone pain; or

  • numbness, tingling, weakness, or paralysis.

Other, less serious side effects may be more likely to occur. Talk to your doctor if you experience

  • hot flashes;

  • increased blood pressure;

  • impotence;

  • nausea or vomiting;

  • dizziness;

  • headache; or

  • pain at the injection site.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect triptorelin?

It is not known whether triptorelin will interact with other medicines. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products during treatment with triptorelin.

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