Before taking tacrine, tell your doctor if you have heart disease or a heart rhythm disorder such as "sick sinus syndrome" (slow heartbeats), an enlarged prostate, urination problems, asthma, obstructive pulmonary disease, or a seizure disorder such as epilepsy.
Tacrine is most effective when taken between meals on an empty stomach, but you may take it with food if it upsets your stomach.It is important to use tacrine regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
Your doctor may occasionally change your dose to make sure you get the best results from this medication.
Tacrine improves the function of nerve cells in the brain. It works by preventing the breakdown of a chemical called acetylcholine (ah see til KO leen). People with dementia usually have lower levels of this chemical, which is important for the processes of memory, thinking, and reasoning.
Tacrine is used to treat mild to moderate dementia caused by Alzheimer's disease.
Tacrine may also be used for purposes other than those listed in this medication guide.
Before taking tacrine, tell your doctor if you are allergic to any drugs, or if you have:
heart disease;
a heart rhythm disorder such as "sick sinus syndrome" (slow heartbeats);
a history of stomach ulcers;
an enlarged prostate or urination problems;
epilepsy or other seizure disorder; or
asthma or chronic obstructive pulmonary disease (COPD).
If you have any of these conditions, you may not be able to use tacrine, or you may need dosage adjustments or special tests during treatment.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether tacrine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.![]() |
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