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sulfinpyrazone
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(sul fin PEER a zone)

What is the most important information I should know about sulfinpyrazone?

To reduce the risk that kidney stones will form, drink at least 8 to 10 full glasses (8 ounces) of fluid every day, unless your doctor tells you not to. Take sulfinpyrazone with food, milk, or an antacid to lessen stomach upset. Do not take aspirin, salsalate (Disalcid), magnesium salicylate (Magan, Doan's), choline and magnesium salicylate (Trilisate), or other aspirin-like products without the approval of your doctor. These products decrease the effects of sulfinpyrazone. Taking one aspirin a day to reduce the risk of a heart attack is usually acceptable. Talk to your doctor.

What is sulfinpyrazone?

Sulfinpyrazone reduces the amount of uric acid in your body by causing more uric acid to be passed out in your urine. Sulfinpyrazone also has other effects in the body that are important in the treatment of gout.

Sulfinpyrazone is used to treat gout and gouty arthritis.

Sulfinpyrazone may also be used for purposes other than those listed in this medication guide.

Who should not take sulfinpyrazone?

Before taking this medication, tell your doctor if you

  • have ever had an allergic reaction to sulfinpyrazone,

  • have kidney disease or poorly functioning kidneys,

  • have kidney stones,

  • have an ulcer in your stomach,

  • have blood problems, or

  • are on high-dose aspirin or salicylate therapy.

Sulfinpyrazone is in the FDA pregnancy category C. This means that it is not known whether sulfinpyrazone will harm an unborn baby. Do not take sulfinpyrazone without first talking to your doctor if you are pregnant. It is also not known whether sulfinpyrazone passes into breast milk. Do not take sulfinpyrazone without first talking to your doctor if you are breast-feeding a baby.

How should I take sulfinpyrazone?

Take sulfinpyrazone exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose of sulfinpyrazone with a full glass of water. Also, to reduce the risk that kidney stones will form, drink at least 8 to 10 full glasses (8 ounces) of fluid every day, unless your doctor tells you not to. Take sulfinpyrazone with food, milk, or an antacid to lessen stomach upset. If nausea, vomiting, or loss of appetite is severe or persistent, consult your doctor.

Do not stop taking this medication without the approval of your doctor.

Store sulfinpyrazone at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a sulfinpyrazone overdose include nausea, vomiting, diarrhea, stomach pain, poor coordination, difficulty breathing, seizures, and coma. An overdose of sulfinpyrazone can result in death.

What should I avoid while taking sulfinpyrazone?

Do not take aspirin, salsalate (Disalcid), magnesium salicylate (Magan, Doan's), choline and magnesium salicylate (Trilisate), or other aspirin-like products unless your doctor approves. These products decrease the effects of sulfinpyrazone. Taking one aspirin a day to reduce the risk of a heart attack is usually acceptable.

Follow your doctor's recommendations about diet.

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