Drug Notebook

FDA Alerts

  • Tumorigenic in chronic toxicity studies in rats. Use for FDA-approved indications; avoid unnecessary use.
  • Spironolactone/hydrochlorothiazide fixed combination not indicated for initial therapy of edema or hypertension. Individualize dosage. If the fixed combination represents the dosage so determined, its use may be more convenient in patient management. The treatment of hypertension and edema is not static but must be reevaluated as conditions in each patient warrant. (See Dosage and Administration.)

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spironolactone
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What other drugs will affect spironolactone?

Before taking this medication, tell your doctor if you are using any of the following drugs:

This list is not complete and there may be other drugs that can interact with spironolactone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about spironolactone.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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