• chest pain, fast or pounding heartbeats, tremors, shaking, or restless feeling;

• wheezing, choking, or other breathing problems after using this medication;

• skin rash, bruising, severe tingling, numbness, pain, muscle weakness; or

• worsening asthma symptoms.

Less serious side effects may include:

• headache, dizziness, lightheadedness, or insomnia;

• sweating;

• nausea, vomiting, or diarrhea; or

• dry mouth or throat irritation.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect salmeterol inhalation?

Before using salmeterol inhalation, tell your doctor if you are using any of the following drugs:

• diuretics (water pills);
• a beta-blocker such as atenolol (Tenormin), metoprolol (Lopressor), propranolol (Inderal), acebutolol (Sectral), bisoprolol (Zebeta), carteolol (Cartrol), carvedilol (Coreg), labetalol (Normodyne, Trandate), nadolol (Corgard), or pindolol (Visken);

• antidepressants such as amitriptyline (Elavil), nortriptyline (Pamelor), desipramine (Norpramin), or imipramine (Tofranil);

• an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam);

• caffeine, a diet medicine, or a decongestant; or

• aminophylline (Truphylline), theophylline (Slo-Bid, Theobid, TheoDur), and others.

This list is not complete and there may be other drugs that can interact with salmeterol inhalation. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about salmeterol inhalation.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.