Drug Notebook
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rizatriptan
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(ry zah TRIP tin)
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What are the possible side effects of rizatriptan?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using rizatriptan and call your doctor at once if you have any of these serious side effects:
  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;

  • sudden numbness or weakness, especially on one side of the body;

  • sudden headache, confusion, problems with vision, speech, or balance;

  • fast heart rate, agitation, muscle stiffness, hallucinations, lack of coordination, with nausea, vomiting, or diarrhea;

  • sudden and severe stomach pain and bloody diarrhea; or

  • numbness or tingling and a pale or blue-colored appearance in your fingers or toes.

Less serious side effects may include:

  • dry mouth, upset stomach;

  • mild headache (not a migraine);

  • feeling too warm or too cold;

  • tremors, confusion;

  • warmth, redness, or tingling under your skin;

  • feeling of pain or pressure in your neck and throat; or

  • weakness, dizziness, sleepiness.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect rizatriptan?

Before using rizatriptan, tell your doctor if you are using any of the following drugs:

  • propranolol (Inderal, InnoPran);

  • an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor); or

  • another migraine medicine such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), or zolmitriptan (Zomig).

This list is not complete and there may be other drugs that can interact with rizatriptan. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about rizatriptan.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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