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Generic Name: penicillin

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treats Rat-bite Fever, Skin or Soft Tissue Infection, Cutaneous Bacillus anthracis, Syphilis, Pneumo... more

FDA Alerts

Penicillin G benzathine (Bicillin^® C-R, Bicillin^® C-R 900/300), penicillin G procaine, and fixed combination containing penicillin G benzathine and penicillin G procaine (Bicillin^® L-A) are administered by deep IM injection only and should not be injected IV or admixed with other IV solutions.
Prior to administration of penicillin G benzathine, penicillin G procaine, or fixed combination of penicillin G benzathine and penicillin G procaine, carefully read the warnings, adverse reactions, and dosage and administration sections of the prescribing information.
Inadvertent IV administration of penicillin G benzathine has been associated with cardiorespiratory arrest and death.

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(pen i SILL in G po TASS ee um)

What happens if I miss a dose?

Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include seizure (convulsions).

What should I avoid while taking penicillin G potassium ?

Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using penicillin G potassium.

What are the possible side effects of penicillin G potassium ?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

swelling, bruising, or irritation where the injection was given;
headache with nausea, vomiting, and tiredness;
a red, blistering, peeling skin rash;
chills, fever, swelling, joint or muscle pain, and confusion;
pale skin, easy bruising or bleeding, unusual weakness;
seizure (convulsions); or
uneven heartbeats.

Less serious side effects may include:

twitching or muscle spasm; or
mild skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect penicillin G potassium ?

Before using this medication, tell your doctor if you are using any of the following drugs:

a tetracycline antibiotic, such as demeclocycline (Declomycin, Ledermycin), doxycycline (Adoxa, Doryx, Vibramycin, Periostat), minocycline (Minocin), or tetracycline (Broadspec, Panmycin, Sumycin);
a sulfa drug such as sulfamethoxazole (Bactrim, Cotrim, Gantanol, Septra, Sulfatrim), or sulfisoxazole (Gantrisin); or
a macrolide antibiotic such as aztihromycin (Zithromax), clarithromycin (Biaxin), dirithromycin (Dynabac), erythromycin (E.E.S., Ery-Tab, Erythrocin, E-Mycin, troleandomycin (Tao).

This list is not complete and there may be other drugs that can interact with penicillin G potassium. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about penicillin G potassium.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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