Drug Notebook
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oxycodone
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(ox i KOE done)
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What is the most important information I should know about oxycodone?

Oxycodone may be habit-forming and should be used only by the person it was prescribed for. Oxycodone should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not drink alcohol while you are taking oxycodone. Dangerous side effects or death can occur when alcohol is combined with a narcotic pain medicine. Check your food and medicine labels to be sure these products do not contain alcohol. Never take more than your prescribed dose of oxycodone. Tell your doctor if the medicine seems to stop working as well in relieving your pain. Oxycodone can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Do not stop using oxycodone suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.

What is oxycodone?

Oxycodone is in a group of drugs called narcotic pain relievers. It is similar to morphine.

Oxycodone is used to treat moderate to severe pain. The extended-release form of this medication is for around-the-clock treatment of pain. Oxycodone is not for treating pain just after a surgery unless you were already taking oxycodone before the surgery.

Oxycodone may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using oxycodone?

Do not use this medication if you have ever had an allergic reaction to a narcotic medicine (examples include methadone, morphine, Oxycontin, Darvocet, Percocet, Vicodin, Lortab, and many others), or to a narcotic cough medicine that contains codeine, hydrocodone, or dihydrocodeine.

You should also not take oxycodone if you are having an asthma attack or if you have a bowel obstruction called paralytic ileus.

Oxycodone may be habit-forming and should be used only by the person it was prescribed for. Oxycodone should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Before using oxycodone, tell your doctor if you are allergic to any drugs, or if you have:

FDA pregnancy category C. This medication may be harmful to an unborn baby, and could cause addiction or withdrawal symptoms in a newborn. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Oxycodone can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more sensitive to the effects of this medicine.
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FDA Alerts

    Abuse Potential
  • Schedule II controlled substance with abuse liability similar to morphine.
  • Potential for abuse in a manner similar to other legal or illicit opiates. Consider abuse potential when prescribing or dispensing oxycodone extended-release tablets (e.g., OxyContin®) in situations where the clinician or pharmacist is concerned about increased risk of misuse, abuse, or diversion.

    Intended Uses of Extended-release Tablets (e.g., OxyContin®)
  • Oxycodone hydrochloride extended-release tablets (e.g., OxyContin®) are a controlled-release oral formulation indicated for the management of moderate to severe pain when a continuous, around-the-clock analgesic is needed for an extended period of time.
  • Oxycodone hydrochloride extended-release tablets (e.g., OxyContin®) are not intended for use as a prn analgesic.
  • Only use the 80- and 160-mg formulations in opiate-tolerant patients. These strengths may cause fatal respiratory depression when administered to patients not previously exposed to opioids. (See Dosage and Administration.)

    Overdose Risk with Improper Administration of Extended-release Tablets (e.g., OxyContin®)
  • Oxycodone hydrochloride extended-release tablets are to be swallowed whole and are not to be broken.
  • Chewing, crushing, or dissolving the extended-release tablets could result in rapid release and absorption of a potentially fatal dose of oxycodone hydrochloride.

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