• muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, nausea with vomiting;

• fast, slow, or uneven heart rate;

• blue lips or fingernails, mottled skin;

• urinating less than usual or not at all;

• irritation of the skin or vein where the medicine is injected;

• sudden numbness or weakness, especially on one side of the body; or

• sudden headache, confusion, problems with vision, speech, or balance.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect norepinephrine?

Before receiving norepinephrine, tell your doctor if you are using any of the following drugs:

• blood pressure medications;

• an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate); or

• an antidepressant such as amitriptyline (Elavil, Etrafon), amoxapine (Ascendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil).

If you are using any of these drugs, you may not be able to receive norepinephrine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect norepinephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist has information about norepinephrine written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.