• increased blood pressure (severe headache, blurred vision);

• seizure (convulsions);

• feeling light-headed, fainting;

• pounding heartbeat;

• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling; or

• hallucinations.

Other less serious side effects are more likely to occur, such as:

• nausea, vomiting, diarrhea;

• leg cramps;

• dizziness;

• ringing in your ears;

• stuffy nose; or

• unpleasant taste in your mouth.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect methylergonovine?

Before taking methylergonovine, tell your doctor if you are using any of the following drugs:

• zileuton (Zyflo);

• antibiotics such as erythromycin (Ery-Tab, Erythrocin, E.E.S), clarithromycin (Biaxin), troleandomycin (Tao);

• fluoxetine (Prozac), fluvoxamine (Luvox);

• clotrimazole (Mycelex Troche), fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), voriconazole (Vfend);

• other ergot medicines such as methysergide (Sansert), ergotamine (Ergostat, Medihaler, Cafergot, Ercaf, Wigraine), or dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray); or

• HIV medicines such as delaviridine (Rescriptor), indinavir (Crixivan), ritonavir (Norvir), saquinavir (Invirase), or nelfinavir (Viracept).

If you are using any of these drugs, you may not be able to use methylergonovine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect methylergonovine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has more information about methylergonovine written for health professionals that you may read.

What does my medication look like?

Methylergonovine is available with a prescription under the brand name Methergine. Other brand or generic forms may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.