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What are the possible side effects of levonorgestrel?

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

• possible blood clot in the lung (shortness of breath or pain in the chest);

• possible blood clot in an arm or leg (pain, redness, swelling, or numbness of an arm or leg);

• headaches with a change in pattern, severity, or length, or that are unending in nature or accompanied by changes in vision;

• high blood pressure (severe headache, flushing, blurred vision); or

• liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue).

• infection at the insertion site;

• pain, numbness, or tingling in the arm with the implanted capsules; or

• movement of the capsules under the skin.

Other, less serious side effects may be more likely to occur. Talk to your doctor if you experience

• breakthrough, heavy, or prolonged menstrual bleeding;

• lack of menstrual bleeding;

• pain, swelling, or bruising at the insertion site;

• headache or dizziness;

• nausea;

• breast tenderness;

• changes in weight or appetite;

• oily skin or acne; or

• changes in hair growth.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect levonorgestrel?

Other medications may decrease the effectiveness of levonorgestrel. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products, while using levonorgestrel.

Where can I get more information?

Your pharmacist has additional information about levonorgestrel written for health professionals that you may read.

What does my medication look like?

Levonorgestrel is available with a prescription under the brand name Norplant System. Other brand name or generic formulations may also be available. Ask your pharmacist any questions you might have about this medication, especially if it is new to you.

• Norplant System-six capsules for implantation each containing 36 mg of levonorgestrel

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.