What is the most important information I should know about itraconazole?
Do not take this medication if you are allergic to itraconazole or similar medications
such as
fluconazole (
Diflucan) or
ketoconazole (
Nizoral), if you have ever had congestive heart
failure, or if you are pregnant or may become pregnant during treatment.
You should not take itraconazole together with cisapride (Propulsid), dihydroedrgotamine
(D.H.E. 45, Migranal), dofetilide (Tikosyn), ergonavine (Ergotrate), ergotamine (Ergomar),
lovastatin (Altocor, Altoprev, Mevacor), methylergonovine (Methergine), midazolam (Versed),
nisoldipine (Sular), pimozide (Orap), quinidine (Quinaglute, Quinidex, Quin-Release),
simvastatin (Zocor), or triazolam (Halcion).
Other drugs that should not be taken together with itraconazole include astemizole
(Hismanal), or levomethadyl Orlaam) (these drugs are no longer available in the U.S.).
There are many other medicines that can interact with itraconazole. Tell your doctor about all the prescription and over-the-counter medications you use.
This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not
start using a new medication without telling your doctor. Keep a list with you of all the
medicines you use and show this list to any doctor or other healthcare provider who treats you.
Before taking itraconazole, tell your doctor if you have heart disease, a history of stroke, a
heart rhythm disorder, kidney or liver disease, a breathing disorder, cystic fibrosis, or a history of
"Long QT syndrome."
Itraconazole capsules should not be used in place of itraconazole oral solution
(liquid) if that is what your doctor has prescribed. Make sure you have received the correct type
of this medication at the pharmacy and ask the pharmacist if you have any questions.
Take this medication for the entire length of time prescribed by your doctor. Your
symptoms may get better before the infection is completely treated. Call your doctor if your
symptoms do not improve.
What is itraconazole?
Itraconazole is an antifungal antibiotic.
Itraconazole is used to treat infections caused by fungus, which can invade any part of the
body including the lungs, mouth or throat, toenails, or fingernails.
Itraconazole may also be used for other purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking itraconazole?
Do not take this medication if you are allergic to itraconazole or similar medications
such as fluconazole (Diflucan) or ketoconazole (Nizoral), if you have ever had congestive heart
failure, or if you are pregnant or planning to become pregnant during treatment.
The following drugs should not be taken together with itraconazole:
-
cisapride (Propulsid);
-
dofetilide (Tikosyn);
-
nisoldipine (Sular);
-
pimozide (Orap);
-
quinidine (Quinaglute, Quinidex, Quin-Release);
-
lovastatin (Altocor, Altoprev, Mevacor) or simvastatin
(Zocor);
-
midazolam (Versed) or triazolam (Halcion);
-
ergot medicines such as dihydroedrgotamine (D.H.E. 45,
Migranal), ergonavine (Ergotrate), ergotamine (Ergomar, Cafergot, Ercaf, Migergot), or
methylergonovine (Methergine); or
-
(these drugs are no longer available in the U.S.) astemizole
(Hismanal), or levomethadyl Orlaam).
Before taking itraconazole, tell your doctor if you are allergic to any
drugs, or if you have:
-
heart disease, a heart rhythm disorder, circulation problems, or a
history of stroke;
-
chronic obstructive pulmonary disease (COPD) or other
breathing disorder;
-
kidney disease;
-
liver disease;
-
cystic fibrosis; or
-
a personal or family history of "Long QT syndrome."
If you have any of these conditions, you may need a dose adjustment
or special tests to safely take itraconazole.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell
your doctor if you are pregnant or plan to become pregnant during treatment.
Itraconazole passes into breast milk and can harm a nursing baby. Do not use this
medication without telling your doctor if you are breast-feeding a baby.
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