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What is the most important information I should know about grepafloxacin?

Grepafloxacin nasal was withdrawn from the U.S. market in 1999.

Take all of the grepafloxacin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Drink plenty of extra fluids every day while taking grepafloxacin. Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 4 hours before or 4 hours after a dose of grepafloxacin. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of grepafloxacin can greatly decrease the effects of the antibiotic.

What is grepafloxacin?

Grepafloxacin nasal was withdrawn from the U.S. market in 1999.

Grepafloxacin is an antibiotic in a class of drugs called fluoroquinolones. Grepafloxacin fights bacteria in your body.

Grepafloxacin is used to treat various types of bacterial infections.

Grepafloxacin may also be used for purposes other than those listed in this medication guide.

Who should not take grepafloxacin?

Before taking this medication, tell your doctor if you have

• liver disease or

• any kind of heart disease or heart problem.

You may not be able to take grepafloxacin, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Grepafloxacin may increase the risk of seizures if you have an existing seizure disease.

Grepafloxacin is in the FDA pregnancy category C. This means that it is not known whether grepafloxacin will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. Grepafloxacin passes into breast milk and may harm a nursing infant. It may affect bone development. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. Grepafloxacin should not be taken by children under 18 years of age. It may interfere with bone development.

How should I take grepafloxacin?

Take grepafloxacin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water (8 ounces). Drink several extra glasses of fluid each day to prevent the formation of grepafloxacin crystals in your urine.

Grepafloxacin may be taken with or without food.

Take grepafloxacin at evenly spaced intervals. Follow your doctor's instructions.

Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 4 hours before or 4 hours after a dose of grepafloxacin. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of grepafloxacin can greatly decrease the effects of the antibiotic. Take all of the grepafloxacin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

Seek emergency medical attention.

The most common symptom of a grepafloxacin overdose is irregular or slow heartbeats.