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What is the most important information I should know about glycopyrrolate?

Use caution when driving, operating machinery, or performing other hazardous activities. Glycopyrrolate may cause dizziness, drowsiness, or blurred vision. If you experience dizziness, drowsiness, or blurred vision, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking glycopyrrolate.

Avoid becoming overheated in hot weather. Glycopyrrolate increases the risk of heat stroke because it causes decreased sweating.

What is glycopyrrolate?

Glycopyrrolate reduces the secretions of certain organs in the body.

Glycopyrrolate helps to control conditions such as peptic ulcers that involve excessive stomach acid production.

The injectable form of glycopyrrolate is also used to reduce saliva, nasal, lung, and stomach secretions and to help control heart rate during surgery.

Glycopyrrolate may also be used for purposes other than those listed in this medication guide.

Who should not take glycopyrrolate?

Do not take glycopyrrolate if you have

• kidney disease;

• a blockage of your urinary tract (difficulty urinating);

• a blockage in your intestines, severe ulcerative colitis, or ulcerative colitis complicated by toxic megacolon;

• glaucoma; or

• myasthenia gravis.

Before taking this medication, tell your doctor if you have

• numbness or tingling in your hands or feet;

• liver disease;

• ulcerative colitis;

• thyroid problems;

• high blood pressure, an irregular heartbeat, or any type of heart disease;

• hiatal hernia or reflux disease;

• enlargement of the prostate; or

• asthma, chronic lung disease, or allergies.

You may not be able to take glycopyrrolate, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

It is not known whether glycopyrrolate will harm an unborn baby. Do not take glycopyrrolate without first talking to your doctor if you are pregnant. It is not known whether glycopyrrolate passes into breast milk. Do not take glycopyrrolate without first talking to your doctor if you are breast-feeding a baby.

How should I take glycopyrrolate?

Take glycopyrrolate exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Glycopyrrolate is usually taken two or three times a day. Follow your doctor's instructions.

Store glycopyrrolate at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a glycopyrrolate overdose include headache; nausea; vomiting; dry mouth; difficulty swallowing; blurred vision; dilated pupils; hot, dry skin; dizziness; drowsiness; confusion; anxiety; seizures; weak pulse; and an irregular heartbeat.

What should I avoid while taking glycopyrrolate?

Use caution when driving, operating machinery, or performing other hazardous activities. Glycopyrrolate may cause dizziness, drowsiness, or blurred vision. If you experience dizziness, drowsiness, or blurred vision, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking glycopyrrolate.

Avoid becoming overheated in hot weather. Glycopyrrolate increases the risk of heat stroke because it causes decreased sweating.