Call your doctor at once if you have any of these serious side effects:

• pale skin, easy bruising or bleeding, unusual weakness;

• urinating less than usual or not at all;

• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;

• sudden numbness or weakness, especially on one side of the body;

• sudden headache, confusion, problems with vision, speech, or balance;

• fever, chills, body aches, flu symptoms;

• white patches or sores inside your mouth or on your lips;

• pain, swelling, or skin changes where the needle was placed;

• hearing problems;

• blood in your urine; or

• breathing problems.

Less serious side effects may be more likely to occur, such as:

• mild nausea, vomiting, upset stomach;

• diarrhea or constipation;

• swelling in your hands, ankles, or feet;

• skin rash;

• numbness or tingly feeling;

• drowsiness; or

• hair loss.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect gemcitabine?

There may be other drugs that can affect gemcitabine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your healthcare provider may have additional information about gemcitabine that you may read.

What does my medication look like?

Gemcitabine is available with a prescription under the brand name Gemzar. Other brand or generic formulations may also be available. Ask your healthcare provider or pharmacist any questions you have about this medication, especially if it is new to you.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.