Symptoms of an ergotamine overdose include nausea, vomiting, weakness, muscle pain, numbness in your fingers or toes, gangrene, itching, confusion, drowsiness, convulsions, and possibly death.
Do not take more than three tablets in a 24-hour period. Do not take more than five tablets in 7 days. If your symptoms are not being adequately treated, talk to your doctor.
an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
chest pain;
numbness or tingling in the fingers or toes;
muscle pain in the arms or legs;
leg weakness;
changes in heart rate;
swelling; or
itching.
Other, less serious side effects may also occur. Continue to take ergotamine and talk to your doctor if you experience nausea or vomiting.
Ergotamine may be habit forming when used for long periods of time. Larger doses may be needed for headache relief, and withdrawal effects may occur when treatment with ergotamine is stopped.Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
another medication that contains an ergot compound such as Ergomar, D.H.E., or D.H.E. Nasal;
another migraine headache medicine such as almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), zolmitriptan (Zomig), rizatriptan (Maxalt), or naratriptan (Amerge)--these medicines must not be taken within 24 hours of a dose of ergotamine;
a selective serotonin reuptake inhibitor (SSRI) such as citalopram (Celexa), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), sertraline (Zoloft), or paroxetine (Paxil);
a beta-blocker (medicines used to treat high blood pressure, irregular heartbeats, and other heart conditions) such as carteolol (Cartrol), carvedilol (Coreg), labetalol (Normodyne, Trandate), nadolol (Corgard), pindolol (Visken), propranolol (Inderal), sotalol (Betapace), or timolol (Blocadren);
an HIV/AIDS medicine such as amprenavir (Agenerase), delavirdine (Rescriptor), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir), or saquinavir (Invirase, Fortovase);
the antibiotics erythromycin (Ery-Tab, E.E.S., E-Mycin, Eryc, others) or clarithromycin (Biaxin);
the antifungal medicines itraconazole (Sporanox) or ketoconazole (Nizoral);
cimetidine (Tagamet, Tagamet HB); or
Drugs other than those listed here may also interact with ergotamine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.
Your pharmacist has more information about ergotamine written for health professionals that you may read.
Ergotamine is available with a prescription under the brand names Ergostat and Ergomar. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.
Ergostat 2 mg--sublingual, orange tablets
Ergomar 2 mg-round, green tablets
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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