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Drug Notebook

Generic Name: clindamycin

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A lincomycin derivative - used forPerinatal Group B Streptococcal Disease and Bacterial Endocarditis... more

FDA Alerts

Diarrhea and Colitis

Clostridium difficile-associated diarrhea and colitis (antibiotic-associated pseudomembranous colitis) has been reported with nearly all anti-infectives, including clindamycin, and may range in severity from mild to life-threatening. Anti-infectives alter normal flora of the colon and may permit overgrowth of clostridia; a toxin produced by C. difficile is one primary cause of antibiotic-associated colitis.
It is important to consider a diagnosis of C. difficile-associated diarrhea and colitis in patients who develop diarrhea subsequent to clindamycin treatment. Diarrhea, colitis, and pseudomembranous colitis have been observed to begin up to several weeks after cessation of clindamycin therapy.
After a diagnosis of C. difficile-associated diarrhea and colitis has been established, initiate therapeutic measures.

Mild cases usually respond to drug discontinuation alone.

In moderate to severe cases, consideration should be given to management with fluids and electrolytes, protein supplementation, and treatment with an anti-infective clinically effective against C. difficile colitis. (See Superinfection/Clostridium difficile-associated Colitis under Cautions.)
Because clindamycin has been associated with severe colitis (potentially fatal), it should be reserved for treatment of serious infections when less toxic anti-infectives are inappropriate.
Do not use for nonbacterial infections.

Media Gallery

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Cleocin HCl
CLEOCIN 300 mg / CLEOCIN 300 mg 300 mg	CLEOCIN 150MG / CLEOCIN 150MG 150 mg
Clindamycin Hydrochloride
cor 153 cor 153 / cor 153 cor 153 150 mg	DAN 5708 / DAN 5708 150 mg	93 3171 / 93 3171 150 mg	cor 154 cor 154 / cor 154 cor 154 300 mg
RX693 RX693 / RX693 RX693 300 mg	DAN 3120 / DAN 3120 300 mg	G 150 mg / 3328 150 mg

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(klin da MYE sin)

What does my medication look like?

Clindamycin is available with a prescription under the brand name Cleocin. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Cleocin 75 mg--green capsules
Cleocin 150 mg--light-blue and green capsules
Cleocin 300 mg--light-blue capsules

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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