• diarrhea that is watery or bloody;

• severe pain, irritation, or skin changes where the needle was placed;

• skin rash, bruising, severe tingling, numbness, pain, muscle weakness;

• uneven heartbeats;

• fever, chills, body aches, flu symptoms;

• easy bruising or bleeding, unusual weakness;

• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;

• seizure (black-out or convulsions); or

• jaundice (yellowing of the eyes or skin).

Less serious side effects are more likely to occur, such as:

• pain, irritation, or hardening where the injection was given;

• stomach pain, nausea, vomiting;

• headache; or

• vaginal itching or discharge.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect cefotaxime injection?

Before using cefotaxime, tell your doctor if you are using any of the following drugs:

• an antibiotic such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), neomycin (Mycifradin, Neo-Fradin, Neo-Tab), netilmicin (Netromycin), streptomycin, or tobramycin (Nebcin, Tobi).

If you are using any of these drugs, you may not be able to use cefotaxime, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect cefotaxime. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist has information about cefotaxime written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.