Use only the liquid form of this medicine in a child younger than 13 years old. Do not give atropine and diphenoxylate tablets to a child under 13.

What is atropine and diphenoxylate?

Atropine affects the body in many different ways, such as reducing spasms in the bladder, stomach, and intestines.

Diphenoxylate is an antidiarrheal medication.

The combination of atropine and diphenoxylate is used to treat diarrhea.

Atropine and diphenoxylate may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking atropine and diphenoxylate?

• jaundice (yellowing of your skin or eyes caused by a liver disorder);

• diarrhea that is caused by bacteria; or

• diarrhea caused by taking an antibiotic.

Before taking atropine and diphenoxylate, tell your doctor if you are allergic to any drugs, or if you have:

• blocked intestines;

• an intestinal disorder such as ulcerative colitis or Crohn's disease;

• liver disease;
• kidney disease;

• heart disease, heart rhythm problems, or high blood pressure;

• glaucoma;

• Down's syndrome;

• a thyroid disorder;

• problems with urination;

• an enlarged prostate;

• asthma or other lung problems; or

• if you are dehydrated;

If you have any of these conditions, you may need a dose adjustment or special tests to safely take atropine and diphenoxylate.