• unusual risk-taking behavior, decreased inhibitions, no fear of danger;

• depressed mood, thoughts of suicide or hurting yourself;

• hyperactivity, agitation, hostility, hallucinations;

• feeling light-headed, fainting;

• seizure (convulsions);

• urinating less than usual or not at all;

• muscle twitching, tremor; or

• jaundice (yellowing of the skin or eyes).

Less serious side effects are more likely to occur, such as:

• drowsiness, dizziness, feeling irritable;

• amnesia or forgetfulness, trouble concentrating;

• sleep problems (insomnia);

• muscle weakness, lack of balance or coordination, slurred speech;

• blurred vision;

• nausea, vomiting, constipation, appetite or weight changes;

• dry or watery mouth, increased sweating; or

• loss of interest in sex.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect alprazolam?

Before taking alprazolam, tell your doctor if you are using any of the following drugs:

• birth control pills;

• cimetidine (Tagamet);

• diltiazem (Tiazac, Cartia, Cardizem);

• isoniazid (Nydrazid, Rifamate);

• propoxyphene (Darvon, Darvocet);

• seizure medication;

• antibiotics such as fluconazole (Diflucan), itraconazole (Sporanox) or ketoconazole (Nizoral); or

• antidepressants such as fluvoxamine (Luvox), desipramine (Norpramin), or imipramine (Janimine, Tofranil).

If you are using any of these drugs, you may not be able to use alprazolam, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect alprazolam. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has information about alprazolam written for health professionals that you may read.

What does my medication look like?

Alprazolam is available with a prescription under the brand names Xanax and Niravam. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.