• Basic Info
• Top Questions
• Clinical Info
• Interactions

Before receiving this medicine, tell your doctor if you also use:

• digoxin (digitalis, Lanoxin);

• lithium (Eskalith, Lithobid);

• thyroxine; or

• a diuretic (water pill) such as triamterene (Dyrenium, Maxzide, Dyazide), spironolactone (Aldactone), or amiloride (Midamor).

This list is not complete and there may be other drugs that can interact with sodium polystyrene sulfonate. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have any of these serious side effects:

• pain or fluttering in your chest;

• uneven heartbeats;

• feeling irritable or confused;

• increased thirst or urination;

• severe muscle weakness;

• inability to move your muscles;

• black, bloody, or tarry stools;

• pain in your lower stomach or rectum; or

• swelling, rapid weight gain.

Less serious side effects may include:

• diarrhea or constipation;

• nausea or vomiting;

• upset stomach; or

• loss of appetite.

This list is not complete and other side effects may occur. Tell your doctor about any unusual or bothersome side effect.