Before taking sodium bicarbonate, tell your doctor if you are taking
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mecamylamine (Inversine);
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methenamine (Mandelamine);
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ketoconazole (Nizoral);
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antacids;
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a tetracycline antibiotic such as tetracycline (Sumycin, Achromycin V, and others), demeclocycline (Declomycin), doxycycline (Vibramycin, Monodox, Doxy, and others), minocycline (Minocin, Dynacin, and others), or oxytetracycline (Terramycin, and others).
You may not be able to take sodium bicarbonate, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
Drugs other than those listed here may also interact with sodium bicarbonate. Talk to your doctor or pharmacist before taking any other prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.
Stop taking sodium bicarbonate and seek emergency medical attention if you experience a rare allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).
Stop taking sodium bicarbonate and notify your doctor if you experience
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nausea or vomiting;
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headache;
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sever mood changes;
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muscle pain;
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swelling of feet, ankles or legs
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decreased appetite;
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unusual tiredness;
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constipation;
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dry mouth or increased thirst; or
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increased urination.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.




