• Basic Info
• Top Questions
• Clinical Info
• Interactions

Do not take codeine with other narcotic pain medications, sedatives, tranquilizers, muscle relaxers, or other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result.

Before taking this medication, tell your doctor if you are using any of the following drugs:

• antidepressants;

• a blood thinner such as warfarin (Coumadin); or

• seizure medication such as carbamazepine (Carbatrol, Tegretol).

This list is not complete and there may be other drugs that can interact with propoxyphene. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• shallow breathing, slow heartbeat;

• feeling light-headed, fainting;

• confusion, hallucinations, unusual thoughts or behavior;

• seizure (convulsions); or

• jaundice (yellowing of the skin or eyes).

Less serious side effects include:

• feeling dizzy or drowsy;

• nausea, vomiting, stomach pain, constipation;

• headache, muscle pain;

• blurred vision; or

• mild skin rash.

This list is not complete and other side effects may occur. Tell your doctor about any unusual or bothersome side effect.