Generic Name: progesterone

There may be other drugs that can interact with progesterone vaginal. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• sudden headache, numbness or weakness (especially on one side of the body), shortness of breath, or problems with vision, speech, or balance;

• chest pain or heavy feeling, pain spreading to the arm or shoulder;

• pain or swelling in one or both legs;

• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

• swelling in your hands, ankles, or feet;

• fever, chills, body aches, flu symptoms;

• a breast lump; or

• symptoms of depression (sleep problems, weakness, mood changes).

Less serious side effects may include:

• mild nausea, vomiting, bloating, stomach cramps;

• diarrhea, constipation, bloating;

• dizziness, drowsiness, tired feeling;

• pain in your vaginal or rectal area;

• pain during intercourse;

• loss of interest in sex;

• breast pain, swelling, or tenderness;

• joint or muscle pain;

• increased night-time urination; or

• vaginal itching, burning, or discharge.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.